Pre-SRS PD-1 Inhibitor Use Linked to Increased Neurological Deficits, Mortality
A multi-institutional study suggests administering PD-1 inhibitors before stereotactic radiosurgery in glioma patients may worsen outcomes.
POD1 Prolactin Levels Predict Long-Term Outcomes After Prolactinoma Resection
Postoperative day 1 prolactin levels help stratify risk for hyperprolactinemia rebound and recurrence, especially with prior dopamine agonist use.
Stereotactic Radiosurgery Improves Tumor Control, Overall Outcomes for Older VS Patients
A retrospective study indicates stereotactic radiosurgery significantly reduces vestibular schwannoma progression and improves neurological outcomes.
Syrinx Shunt Outcomes Vary by Type: Revision Risk vs. Early Neurological Benefit
A retrospective study compares syringopleural, syringosubarachnoid, and syringoperitoneal shunts, detailing revision rates and neurological improvemen
Frontal AVMs Alter fMRI Language Lateralization, Requiring Clinical Caution
A retrospective study indicates that arteriovenous malformations in the frontal lobe significantly affect fMRI-based language lateralization indices.
Occipitotemporal White Matter: Redefining Inferior Longitudinal Fasciculus Components
A combined cadaveric dissection and diffusion tensor imaging study clarifies the anatomical boundaries and subcomponents of key visual and cognitive.
Thrombectomy Improves Functional Independence in Medium-Vessel Occlusion Stroke
A randomized trial shows endovascular thrombectomy increases functional independence but also raises symptomatic intracranial hemorrhage risk in mediu
Intracranial Recordings Map Immediate and Distal Neural Responses to Magnetic Stimulation
A review of human and primate data shows single-pulse TMS excites neurons in 2 milliseconds and modulates networks for up to 40 minutes.
Intra-Arterial Alteplase Improves Recovery After Successful Thrombectomy
Adjunctive thrombolysis increased 90-day functional independence by 15% but was associated with a nearly 6% increase in mortality.
Breast GPA Predicts Intracranial Progression and Survival in Breast Cancer
A large cohort study links local brain control to overall survival, identifying tumor subtype and performance status as key predictors.
Tenecteplase Before Thrombectomy Does Not Improve Late-Window Stroke Outcomes
A phase 3 trial in patients with proximal MCA occlusions found no functional benefit to adding tenecteplase between 4.5 and 24 hours.
Transradial Access Does Not Increase Radiation in Aneurysm Treatment
A comparative study finds no significant difference in radiation dose between radial and femoral routes for endovascular repair.