Astegolimab Reduces COPD Exacerbations in Broad Patient Population
A pooled analysis of two trials shows astegolimab significantly lowers moderate/severe exacerbation rates in patients with frequent COPD…
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Tezepelumab Reduces Exacerbations, Improves Lung Function in Diverse Severe Asthma Cohort
A real-world phase 4 study shows tezepelumab's effectiveness and safety across various severe asthma phenotypes and underrepresented patient groups.
Emergency & Critical Care Daily Digest — May 20, 2026
Start your day with yesterday's most clinically relevant updates, carefully curated for better medical practice.
Catch up with your daily audio briefing on the clinical updates that matter most.
Tirzepatide Reduces Major Kidney Events More Than Dulaglutide
In patients with type 2 diabetes and cardiovascular disease, tirzepatide lowered the risk of renal outcomes by 23% over four years.
Thrombectomy Improves Functional Independence in Medium-Vessel Occlusion Stroke
A randomized trial shows endovascular thrombectomy increases functional independence but also raises symptomatic intracranial hemorrhage risk in mediu
INTEGRATE: international guidelines for the algorithmic treatment of schizophrenia
Algorithmic treatment of schizophrenia
Trial Watch
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Favipiravir Safe, Well-Tolerated for Mild-to-Moderate Lassa Fever
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Thrombectomy Improves Functional Independence in Medium-Vessel Occlusion Stroke
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Ensitrelvir Reduces COVID-19 Incidence by 6.1% in Household Contacts
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Telitacicept Reduces Proteinuria in IgA Nephropathy: Phase 3 Interim Analysis
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Intra-Arterial Alteplase Improves Recovery After Successful Thrombectomy
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Tirzepatide Reduces Major Kidney Events More Than Dulaglutide
New Guidelines
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SCCM and ESICM launch 2026 guideline for Sepsis and Septic Shock Management
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AHA and ACC launch 2026 guideline for Acute Pulmonary Embolism in Adults
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AHA and ASA launch 2026 guideline for Acute Ischemic Stroke management
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ACEP launches 2025 clinical policy for Endotracheal Intubation in the Emergency Department
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LANCETP launches 2025 guideline for Algorithmic Treatment of Schizophrenia
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EUSEM launches 2025 guideline for Acute Pain Management in Emergency Situations
Latest
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Pre-SRS PD-1 Inhibitor Use Linked to Increased Neurological Deficits, Mortality
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POGO Score Shows Limited Diagnostic Value in Pediatric Videolaryngoscopy
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Abortion Bans Linked to Shifts in Spontaneous Abortion Management
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Acetate Attenuates Microglial Inflammation in Traumatic Brain Injury Model, Not Sepsis
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Platelet mTOR Pathway Drives Neuropathogenesis in Cerebral Malaria
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Four Clinical Trajectories Identify Distinct Outcomes in Acute Respiratory Failure