Occipitotemporal White Matter: Redefining Inferior Longitudinal Fasciculus Components
A combined cadaveric dissection and diffusion tensor imaging study clarifies the anatomical boundaries and subcomponents of key visual and cognitive.
Social Rank Modulates Empathic Pain via ACC-NAcC Circuit in Mice
A specific glutamatergic pathway and molecular target influence empathic pain responses based on social hierarchy.
APOE ε2 and ε4 Drive Alzheimer's Risk Through Distinct Molecular Pathways
A multicohort proteomic analysis reveals allele-specific protein signatures influencing Alzheimer's disease risk and progression.
Anti-C5a Antibody STSA-1002 Shows Favorable Safety, Reduced Mortality in ARDS
A phase 1b/2 trial indicates STSA-1002 is well tolerated and associated with lower 28-day mortality in viral pneumonia-induced ARDS.
CTBS to Right DLPFC Reduces Heavy Drinking Relapse Risk in AUD Over 12 Months
Continuous theta-burst stimulation to the right DLPFC lowered heavy-drinking relapse risk in AUD over 12 months in a randomized trial.
Younger Age, Autoimmune Disease Linked to Recurrent, Bilateral Facial Palsy
A retrospective study identifies specific risk factors for recurrent and bilateral facial palsy in Bell's Palsy and Ramsay Hunt Syndrome patients.
ACEP launches 2025 clinical policy for Endotracheal Intubation in the Emergency Department
The new guideline prioritizes physiologic optimization, recommending noninvasive ventilation for preoxygenation and specific induction agents.
EUSEM launches 2025 guideline for Acute Pain Management in Emergency Situations
This updated guideline fundamentally shifts acute pain management in emergency settings towards multimodal, non-opioid first-line therapies.
ERC and ESICM launch 2025 guideline for Post-Resuscitation Care
New guidelines emphasize comprehensive diagnostic imaging, refined temperature control, and a multimodal approach to neurological prognostication.
Dose-Sparing Polio Vaccine Matches Full-Dose Immunogenicity and Safety in Infants
An adjuvanted inactivated poliovirus vaccine with reduced antigen content demonstrates comparable immune response and safety to standard IPV.
AHA and ASA launch 2026 guideline for Acute Ischemic Stroke management
The new guideline introduces tenecteplase as an alternative to alteplase for IV thrombolysis and expands recommendations for pediatric stroke care.
SSRIs Induce Spatially Distinct Molecular Changes in Dorsal Raphe Serotonin Neurons
A mouse study reveals how fluoxetine alters gene expression and neuropeptide levels in specific serotonergic subpopulations.