Tranexamic Acid Efficacy Varies by Breast Procedure Type
A retrospective cohort study clarifies which breast surgeries benefit from tranexamic acid for hematoma prevention.
Chronic Pain Mechanisms Show Distinct Cortical Connectivity Patterns
A study using TMS-EEG identifies neurophysiological differences across nociceptive, neuropathic, and nociplastic pain phenotypes.
THA Approaches Yield Similar Patient Outcomes, Distinct Gait Biomechanics
While patient-reported improvements are consistent across THA approaches, minimally invasive techniques offer specific early gait efficiency.
Amitriptyline Not Superior to Placebo for Leprosy-Related Neuropathic Pain
A randomized controlled trial found amitriptyline did not offer additional analgesia as add-on therapy for neuropathic pain in leprosy.
TMEM106B Variant Delays FTD Onset in GRN Mutation Carriers
A specific genetic variant significantly reduces FTD onset risk and extends median onset age by 14 years in GRN mutation carriers.
Muscle Cramp Impact Index Validated for Multidimensional Symptom Assessment
A new 14-item tool measures how muscle cramps interfere with sleep and daily life across neuromuscular, renal, and hepatic conditions.
Male Facelift Hematoma Rates Similar to Females With Standardized Protocols
A matched cohort analysis indicates that male facelift patients experience comparable hematoma rates to females when modern surgical protocols.
Dupilumab Reduces COPD Hospitalizations, ED Visits, and Corticosteroid Use
A pooled analysis of two phase 3 trials shows dupilumab significantly lowers healthcare utilization and corticosteroid burden in COPD patients.
Selective Early PDA Pharmacotherapy Feasible in Extremely Preterm Infants
A pilot randomized trial demonstrates the feasibility of a targeted medical approach for patent ductus arteriosus in infants under 26 weeks'.
Non-Ischemic Dilated Cardiomyopathy: Higher Prevalence, Complex Genetics
Updated estimates suggest non-ischemic dilated cardiomyopathy affects 1 in 220, driven by diverse genetic and environmental factors.
New Tool Assesses Integrative Oncology Competencies in Trainees
A validated questionnaire helps evaluate baseline clinical skills in integrative oncology among healthcare provider trainees, supporting targeted.
Remote Multicomponent Rehabilitation Does Not Improve Quality of Life for ICU Survivors
A randomized trial found a 6-week remote rehabilitation program did not significantly enhance health-related quality of life at 8 weeks.