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24 stories
  1. Sustained Attention Tasks During MRI Improve Prediction of Autistic Traits
    Nature Mental Health ·Cohort Study · April 22, 2026

    Sustained Attention Tasks During MRI Improve Prediction of Autistic Traits

    Functional imaging during cognitive challenges identifies neural markers of social responsiveness more accurately than resting-state scans.

  2. Grammatical Boundaries Limit Word Prediction Precision in the Human Brain
    Nature Neuroscience ·Cohort Study · April 22, 2026

    Grammatical Boundaries Limit Word Prediction Precision in the Human Brain

    Neural responses to word unpredictability decrease at major phrase boundaries, suggesting language processing prioritizes structure over raw statistic

  3. Venlafaxine Linked to Probable Induction of De Novo Vocal Tics
    Frontiers in Psychiatry ·Case Report · April 22, 2026

    Venlafaxine Linked to Probable Induction of De Novo Vocal Tics

    A case report identifies the first instance of vocal tics following SNRI use, likely due to fronto-striatal dopamine dysregulation.

  4. App-Based Cognitive Tasks Increase Subclinical Mental Health Screening Accuracy to 91%
    Frontiers in Psychiatry ·Diagnostic Accuracy Study · April 22, 2026

    App-Based Cognitive Tasks Increase Subclinical Mental Health Screening Accuracy to 91%

    Combining objective neuropsychological metrics with self-reports identifies subclinical distress more accurately than subjective tools alone.

  5. Algorithm Tracks Patient Signals to Calibrate Psychotherapy Intensity
    Frontiers in Psychiatry ·Consensus Statement · April 21, 2026

    Algorithm Tracks Patient Signals to Calibrate Psychotherapy Intensity

    A four-node framework uses physiological markers and anxiety thresholds to guide real-time clinical decisions and intervention dosing.

  6. Reduced Loss Aversion and Impaired Response Inhibition Distinguish Suicide Attempters
    Frontiers in Psychiatry ·Case-Control Study · April 21, 2026

    Reduced Loss Aversion and Impaired Response Inhibition Distinguish Suicide Attempters

    Cognitive profiling reveals that reduced sensitivity to loss and poor impulse control characterize patients with violent suicide attempts.

  7. Parenting Styles and Distress Tolerance Mediate Adolescent Self-Injury Risk
    Frontiers in Psychiatry ·Cross-Sectional Study · April 21, 2026

    Parenting Styles and Distress Tolerance Mediate Adolescent Self-Injury Risk

    A study of 311 adolescents finds that family dynamics and emotional regulation fully mediate the link between impulsivity and self-harm.

  8. Electroconvulsive Therapy Aids Personality Integration in Adolescent Dissociative Identity Disorder
    Frontiers in Psychiatry ·Case Report · April 21, 2026

    Electroconvulsive Therapy Aids Personality Integration in Adolescent Dissociative Identity Disorder

    A case report details how combined neuromodulation and pharmacotherapy resolved three distinct personality states and severe depression.

  9. Neuropsychiatric Symptoms and CSF Markers Predict General Paresis Outcomes
    Frontiers in Psychiatry ·Cohort Study · April 21, 2026

    Neuropsychiatric Symptoms and CSF Markers Predict General Paresis Outcomes

    A 12-month study identifies depression, apathy, and baseline inflammatory markers as key indicators of prognosis in neurosyphilis.

  10. Revised Chinese DARS Validated for Multidimensional Anhedonia Assessment
    Frontiers in Psychiatry ·Diagnostic Accuracy Study · April 21, 2026

    Revised Chinese DARS Validated for Multidimensional Anhedonia Assessment

    A study of 788 psychiatric outpatients confirms a four-factor model for measuring reward deficits across diverse clinical domains.

  11. Nearly 45 Percent of Chinese Primary Teachers Report Anxiety Under New Policy
    Frontiers in Psychiatry ·Cross-Sectional Study · April 21, 2026

    Nearly 45 Percent of Chinese Primary Teachers Report Anxiety Under New Policy

    A cross-sectional study of 3,199 educators identifies advanced degrees and income dissatisfaction as key independent risk factors.

  12. Modern Smartwatches Match Patient-Reported Sleep Duration Within Seven Minutes
    Frontiers in Psychiatry ·Cross-Sectional Study · April 21, 2026

    Modern Smartwatches Match Patient-Reported Sleep Duration Within Seven Minutes

    Newer wearable models show high concordance with self-reported sleep duration but struggle to capture subjective sleep quality extremes.

  13. One in Five Southern California College Students Report Human Trafficking
    Frontiers in Psychiatry ·Cross-Sectional Study · April 21, 2026

    One in Five Southern California College Students Report Human Trafficking

    A 12-campus survey identifies high trafficking rates linked to sexually transmitted infections, food insecurity, and academic barriers.

  14. Antipsychotics Rarely Cause Persistent QTc Prolongation in Children and Adolescents
    Frontiers in Psychiatry ·Cohort Study · April 21, 2026

    Antipsychotics Rarely Cause Persistent QTc Prolongation in Children and Adolescents

    A cohort study of 430 pediatric patients found no severe arrhythmias or QTc intervals over 500 ms during antipsychotic treatment.

  15. Focused Ultrasound Reduces Alcohol Preference and Anxiety in Mice
    Frontiers in Neuroscience ·Animal Study · April 21, 2026

    Focused Ultrasound Reduces Alcohol Preference and Anxiety in Mice

    Low-intensity focused ultrasound targeting the hippocampus mitigates neuronal degeneration and suppresses withdrawal symptoms in a mouse model.

  16. Preclinical Review Links Kratom to Epigenetic Changes and Cardiac Risks
    Translational Psychiatry ·Systematic Review · April 21, 2026

    Preclinical Review Links Kratom to Epigenetic Changes and Cardiac Risks

    Systematic analysis of 20 studies identifies HDAC2 and Rab35 as markers of dependence while highlighting CYP450 and ion channel interference.

  17. Blood-Brain Barrier Integrity Dictates Serum GFAP Accuracy in Cognitive Impairment
    Translational Psychiatry ·Cross-Sectional Study · April 21, 2026

    Blood-Brain Barrier Integrity Dictates Serum GFAP Accuracy in Cognitive Impairment

    A study of 74 patients shows that serum biomarkers only strongly correlate with central pathology when the blood-brain barrier is disrupted.

  18. C4A Complement Pathway Decouples from C1Q in First-Episode Psychosis
    Translational Psychiatry ·Cohort Study · April 21, 2026

    C4A Complement Pathway Decouples from C1Q in First-Episode Psychosis

    A study of 113 patients shows that C4A levels shift independently of C4B in the cerebrospinal fluid during early-stage psychosis.

  19. Exogenous Hormones Associate With Reduced Dementia Risk in UK Biobank Cohort
    Translational Psychiatry ·Cohort Study · April 21, 2026

    Exogenous Hormones Associate With Reduced Dementia Risk in UK Biobank Cohort

    Use of oral contraceptives and hormone replacement therapy correlates with lower rates of Alzheimer's disease and vascular dementia.

  20. Distinct Cortical Thickness Patterns Define Positive and Negative Schizotypy
    Molecular Psychiatry ·Cohort Study · April 21, 2026

    Distinct Cortical Thickness Patterns Define Positive and Negative Schizotypy

    MRI analysis of 2730 healthy adults links subclinical traits to specific neurotransmitter systems and neurodevelopmental disorders.

  21. Ceruloplasmin Deficiency Linked to Fusiform Gyrus Pathology in Autism Subtype
    Molecular Psychiatry ·Cohort Study · April 21, 2026

    Ceruloplasmin Deficiency Linked to Fusiform Gyrus Pathology in Autism Subtype

    Low ceruloplasmin levels drive lipid and myelin imbalances in children with autism and atypical visual processing.

  22. Cannabis Use Blunts Neurocognitive Development in Adolescents
    Neuropsychopharmacology ·Cohort Study · April 21, 2026

    Cannabis Use Blunts Neurocognitive Development in Adolescents

    Longitudinal data and hair toxicology link THC exposure to flattened growth in memory and processing speed from ages 9 to 17.

  23. Systematic Review Evaluates 70 Years of Neuroimaging in Extra-Sensory Perception
    NeuroImage ·Systematic Review · April 21, 2026

    Systematic Review Evaluates 70 Years of Neuroimaging in Extra-Sensory Perception

    Analysis of 143 reports identifies potential electrophysiological markers despite widespread methodological limitations and small samples.

  24. Oral Frailty Affects 69% of Hospitalized Patients With Schizophrenia
    Frontiers in Psychiatry ·Cross-Sectional Study · April 21, 2026

    Oral Frailty Affects 69% of Hospitalized Patients With Schizophrenia

    A machine learning analysis identifies medication non-adherence and hospitalization frequency as key predictors of dental decline.