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The Briefing · Emergency & Critical Care

Continuous newsroom coverage of evidence in Emergency & Critical Care — newest first.

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24 stories
  1. One in Three ICH Patients on Antithrombotics Lack Clinical Indication
    Neurosurgery ·Cohort Study · April 25, 2026

    One in Three ICH Patients on Antithrombotics Lack Clinical Indication

    A retrospective study finds 30.4% of patients with intracranial hemorrhage were taking unindicated anticoagulants or antiplatelets.

  2. Daily Resistance Training and Verticalization Safe During ECMO Support
    Critical Care Medicine ·Cohort Study · April 25, 2026

    Daily Resistance Training and Verticalization Safe During ECMO Support

    A pilot study shows that structured mobility and resistance exercises correlate with improved functional performance in critically ill adults.

  3. Vuzix Head-Mounted Device Scores Highest in Prehospital Stroke Triage Simulation
    Scandinavian Journal of Trauma Resuscitation and Emergency Medicine ·Non-Randomized Controlled Trial · April 25, 2026

    Vuzix Head-Mounted Device Scores Highest in Prehospital Stroke Triage Simulation

    A comparative study finds neurologists prefer head-mounted video quality while paramedics favor smartphone usability for remote triage.

  4. Adolescent Opioid Harms Double Despite Reduced Emergency Department Prescribing
    PEDIATRICS ·Cohort Study · April 25, 2026

    Adolescent Opioid Harms Double Despite Reduced Emergency Department Prescribing

    A decade-long study of 1.2 million visits shows that cutting pediatric opioid prescriptions did not prevent a rise in clinical harms.

  5. Structured Exercise and Resistance Training Safe During ECMO Support
    Critical Care Medicine ·Cohort Study · April 25, 2026

    Structured Exercise and Resistance Training Safe During ECMO Support

    A pilot study of 20 patients shows that intensive twice-daily rehabilitation correlates with improved functional performance and survival.

  6. For-Profit Trauma Centers Increase Redundancy but Fill Critical Access Gaps
    Journal of Trauma: Injury, Infection, and Critical Care ·Cross-Sectional Study · April 25, 2026

    For-Profit Trauma Centers Increase Redundancy but Fill Critical Access Gaps

    Geospatial analysis shows for-profit centers serve 43 million people, often overlapping with existing nonprofit trauma infrastructure.

  7. Ketamine Does Not Reduce 28-Day Mortality Compared With Etomidate
    New England Journal of Medicine ·Randomized Controlled Trial · April 25, 2026

    Ketamine Does Not Reduce 28-Day Mortality Compared With Etomidate

    A randomized trial of 2,365 critically ill adults found no survival benefit for ketamine, despite a higher rate of cardiovascular collapse.

  8. Early Plasma Reduces Mortality in Traumatic Intracranial Hemorrhage
    Journal of Trauma: Injury, Infection, and Critical Care ·Cohort Study · April 24, 2026

    Early Plasma Reduces Mortality in Traumatic Intracranial Hemorrhage

    A retrospective study of 6,183 patients shows a 5% absolute survival drop for every 10-minute delay in plasma during the first half hour.

  9. Recent Psychotropic Initiation and Frequent ER Visits Signal Suicide Risk
    Journal of Affective Disorders ·Case-Control Study · April 24, 2026

    Recent Psychotropic Initiation and Frequent ER Visits Signal Suicide Risk

    A nationwide study identifies mood stabilizer initiation and fragmented emergency care as critical proximal markers of suicide risk.

  10. Indirect Expenses Account for 86 Percent of Trauma Resuscitation Costs
    Journal of Trauma: Injury, Infection, and Critical Care ·Cost-Effectiveness Analysis · April 24, 2026

    Indirect Expenses Account for 86 Percent of Trauma Resuscitation Costs

    A time-driven activity-based costing analysis of 134 patients shows the average 17-minute resuscitation costs $3,628.

  11. RRT Configuration Does Not Impact Complication Rates in VA-ECMO Patients
    Journal of Intensive Care Medicine ·Cohort Study · April 24, 2026

    RRT Configuration Does Not Impact Complication Rates in VA-ECMO Patients

    A retrospective study finds no significant differences in infection or bleeding between integrated and parallel renal replacement circuits.

  12. Low Diaphragm Thickening Fraction at One Hour Predicts Noninvasive Ventilation Failure
    European Journal of Emergency Medicine ·Cohort Study · April 23, 2026

    Low Diaphragm Thickening Fraction at One Hour Predicts Noninvasive Ventilation Failure

    Bedside ultrasound of the diaphragm after 60 minutes of support identifies patients likely to require endotracheal intubation.

  13. Emergency Laparotomy Survivors Face High Readmission and Inconsistent Follow-up
    World Journal of Emergency Surgery ·Cohort Study · April 23, 2026

    Emergency Laparotomy Survivors Face High Readmission and Inconsistent Follow-up

    A multicenter study of 557 patients reveals that nearly 20% return to the hospital within 30 days of discharge.

  14. Noninvasive Fascial Traction Increases Primary Closure Rates in Open Abdomens
    Journal of Trauma: Injury, Infection, and Critical Care ·Cohort Study · April 23, 2026

    Noninvasive Fascial Traction Increases Primary Closure Rates in Open Abdomens

    Adding a traction device to negative pressure therapy reduces the 12-month incisional hernia risk from 63.1% to 14.1%.

  15. Paramedics Rely on Informal Norms for Prehospital Opioid Selection
    Scandinavian Journal of Trauma Resuscitation and Emergency Medicine ·Qualitative Study · April 23, 2026

    Paramedics Rely on Informal Norms for Prehospital Opioid Selection

    Qualitative data from Oslo University Hospital shows 'ambulance truths' and transport logistics drive the choice between fentanyl and morphine.

  16. Targeted Therapies and Prognostic Scoring Improve Acute Liver Failure Outcomes
    Journal of Intensive Care Medicine ·Systematic Review · April 23, 2026

    Targeted Therapies and Prognostic Scoring Improve Acute Liver Failure Outcomes

    Early etiology-specific intervention and validated scoring systems are essential to optimize survival before advanced encephalopathy occurs.

  17. Temperature Management Linked to Lower Brain Disability After In-Hospital Arrest
    Journal of Intensive Care Medicine ·Cohort Study · April 23, 2026

    Temperature Management Linked to Lower Brain Disability After In-Hospital Arrest

    A nationwide cohort study finds targeted cooling reduces the risk of specialist-certified permanent neurological impairment by 15 percent.

  18. Standardized Protocol Alters Medication Use in Pediatric Cannabis Hyperemesis Syndrome
    Pediatric Emergency Care ·Cohort Study · April 23, 2026

    Standardized Protocol Alters Medication Use in Pediatric Cannabis Hyperemesis Syndrome

    Implementation of a clinical pathway increased capsaicin and metoclopramide use while reducing haloperidol dosages in adolescents.

  19. Clinical Pathway Reduces Pediatric CT Use to 22 Percent
    Pediatric Emergency Care ·Cohort Study · April 22, 2026

    Clinical Pathway Reduces Pediatric CT Use to 22 Percent

    A multidisciplinary protocol met national quality benchmarks while cutting emergency department wait times by over 100 minutes.

  20. Paramedic Patella Reduction Reduces Hospital Transport and Dislocation Time
    Prehospital Emergency Care ·Cohort Study · April 22, 2026

    Paramedic Patella Reduction Reduces Hospital Transport and Dislocation Time

    A retrospective analysis of 1,210 patients shows a 91.8% success rate for prehospital reduction, cutting dislocation time by 71 minutes.

  21. Age, Rhythm, and Low-Flow Duration Predict Neurological Recovery After ECPR
    Resuscitation ·Cohort Study · April 22, 2026

    Age, Rhythm, and Low-Flow Duration Predict Neurological Recovery After ECPR

    A 14-year cohort study identifies specific predictors to help clinicians select cardiac arrest patients for extracorporeal resuscitation.

  22. Open-Source AI Models Accurately Classify Pediatric Pneumonia on Radiographs
    Pediatric Emergency Care ·Diagnostic Accuracy Study · April 22, 2026

    Open-Source AI Models Accurately Classify Pediatric Pneumonia on Radiographs

    Large language models match physician adjudication of free-text reports, surpassing traditional machine learning in the emergency department.

  23. Dexmedetomidine Linked to Lower Mortality in ICU Patients With Delirium
    Journal of Intensive Care Medicine ·Cohort Study · April 22, 2026

    Dexmedetomidine Linked to Lower Mortality in ICU Patients With Delirium

    A retrospective analysis of two large databases shows reduced in-hospital and one-year mortality for delirious patients given the sedative.

  24. Subanesthetic Ketamine Improves Depressive Symptoms in Critically Ill Adults
    Journal of Intensive Care Medicine ·Cohort Study · April 22, 2026

    Subanesthetic Ketamine Improves Depressive Symptoms in Critically Ill Adults

    A retrospective study finds three days of low-dose ketamine reduces sadness in ICU patients with minimal hemodynamic impact.