Mindfulness Adjunct Lowers Anxiety Scores in Medicated Adults With GAD
An 8-week mindfulness program added to pharmacotherapy improved clinician-rated anxiety, sleep quality, and psychosocial functioning.
Prefrontal Stimulation Amplifies Placebo Mood Response in Depression
Intermittent theta burst stimulation of the dorsomedial prefrontal cortex modulates the default mode network to enhance expectancy effects.
One-Liter PEG-Ascorbate Improves High-Quality Inpatient Bowel Cleansing
A randomized trial shows very low-volume preparation yields superior right-colon visualization compared to 2-liter and 4-liter regimens.
Manual Pressure Augmentation During Defibrillation Does Not Improve Survival
A randomized trial found that while manual pressure reduces transthoracic impedance, it does not increase survival to hospital discharge.
Restrictive Sepsis Resuscitation Shows No Long-Term Functional Deficits
A randomized trial finds similar cognitive and physical outcomes at 12 months for restrictive versus liberal fluid strategies in sepsis.
Active Support Increases Injury Prevention Program Use in Female Athletes
In-person workshops for coaches tripled the use of injury prevention protocols, though direct impact on ACL and concussion rates remains unclear.
Elective Microaxial Flow Pump Does Not Improve High-Risk PCI Outcomes
A randomized trial finds no clinical benefit and a potential mortality signal with routine mechanical unloading during complex revascularization.
Microaxial Flow Pump Fails to Improve Outcomes in High-Risk PCI
A randomized trial of 300 patients shows elective left ventricular unloading does not reduce major adverse events at 12 months.
Abrocitinib Shows Faster Itch Relief Than Dupilumab in Atopic Dermatitis
A post hoc analysis of JADE trials finds oral JAK1 inhibition reaches an itch-free state sooner, correlating with better sleep and quality of life.
Psychotherapy Shows Large, Durable Effects in Treatment-Resistant Depression
A reanalysis of trial data suggests clinical gains stem from simultaneous psychological shifts rather than sequential changes in defense.
Telehealth Hypnotic Cognitive Therapy Reduces Chronic Pain After Spinal Cord Injury
A randomized trial demonstrates that remote delivery of hypnotic cognitive therapy significantly lowers pain intensity and depression.
Triplet Immunotherapy Shows Durable Response in Relapsed Hodgkin Lymphoma
Adding ipilimumab to nivolumab and brentuximab vedotin may improve long-term disease control for patients deferring stem cell transplant.