Triplet Immunotherapy Shows Durable Response in Relapsed Hodgkin Lymphoma
Adding ipilimumab to nivolumab and brentuximab vedotin may improve long-term disease control for patients deferring stem cell transplant.
APT-Sepsis Program Lowers Maternal Infection Mortality and Morbidity
A cluster-randomized trial of 431,394 women shows a 32% reduction in severe infection-related outcomes using a standardized care bundle.
Cortical Stimulation Reduces Overactive Bladder Symptoms After Stroke
A randomized trial shows low-frequency rTMS improves urinary function and quality of life while lowering societal costs.
Evolocumab Reduces First Cardiovascular Events in High-Risk Diabetes
In patients with diabetes and no known atherosclerosis, adding evolocumab to statins lowered the 5-year risk of major events by 2.1%.
Delayed Angiography Safe in Cardiac Arrest Without ST-Segment Elevation
Five-year COACT trial data show no survival difference between immediate and delayed coronary angiography for resuscitated patients.
Digital Exercise and Interoceptive Training Lower Acute Depression Scores in Young Adults
A randomized trial found significant short-term symptom reduction, though benefits did not persist at one- or three-month follow-up.
Group CBT Reduces Hostile Attribution Bias in Young Adults With ASD Traits
A pilot study finds that targeting social cognitive distortions improves communication and quality of life through distinct pathways.
Group Cognitive Therapy Reduces Negative Symptoms in Early Psychosis
A pilot trial shows rumination-focused therapy added to standard care significantly improves negative symptoms and repetitive thinking.
Iron Bioresorbable Scaffolds Match Metallic Stents for Late Lumen Loss at Two Years
A randomized trial in China finds iron-based scaffolds achieve similar vascular patency and flow to standard stents despite higher revascularization.
Biomarkers Predict Kidney Response to Belimumab in Lupus Nephritis
A Phase 3 post hoc analysis identifies baseline IgA, anti-C1q, and early proteinuria changes as key indicators of treatment success.
Distributed HABIT-ILE Dosing Matches Massed Therapy for Bilateral Cerebral Palsy
Spreading 90 hours of intensive bimanual and lower extremity therapy over 15 weeks yields functional gains equivalent to 3-week programs.
Mim8 Prophylaxis Reduces Bleeding in Hemophilia A with or without Inhibitors
Phase 3 data show weekly or monthly subcutaneous Mim8 significantly lowers bleeding rates compared to on-demand and prior factor therapy.