Low CSF Amyloid-Beta Predicts Intracranial Hemorrhage in CAA Patients
Low levels of amyloid-beta 40 and 42 in cerebrospinal fluid are associated with a sevenfold increase in future symptomatic bleeding risk.
Abdominal Contractions Drive Brain Motion and Fluid Clearance in Mice
A hydraulic link between the abdomen and cranium suggests physical activity mechanically facilitates interstitial fluid drainage.
Responsive Neurostimulation Reduces Focal Seizures by 82% at Three Years
A prospective postapproval study of 324 adults shows real-world seizure reduction exceeds initial clinical trial results.
Sublobectomy Extends Survival in IDH-Wildtype Glioblastoma
A retrospective study shows supramaximal resection within functional limits improves survival without increasing neurological deficits.
Non-Invasive Tools Estimate Intracranial Pressure When Invasive Monitoring Is Contraindicated
A review evaluates ultrasound and imaging techniques to detect intracranial hypertension in patients with coagulopathy or liver failure.
Molecular Markers in Rathke’s Cleft Cysts Correlate With Endocrine Deficits
A retrospective study of 108 patients identifies FOXJ1 and TUBA1A as indicators of hypopituitarism and vasopressin deficiency.
Subthalamic Nucleus Predominantly Facilitates Action in Primate Models
Electrophysiological data show 89 percent of task-related neurons in the subthalamic nucleus promote rather than inhibit motor choices.
Robotic CT-Guided Cannula Placement Shows Sub-Millimeter Precision in Phantom Models
Researchers placed multiple convection-enhanced delivery cannulas in under 30 minutes with high stereotactic accuracy.
Brain-Responsive Neurostimulation Reduces Focal Seizures by 82% at Three Years
A prospective real-world study shows higher seizure reduction rates and lower SUDEP risk than observed in initial clinical trials.
High-Ratio Plasma Resuscitation Reduces Mortality in Moderate Traumatic Brain Injury
A large database analysis suggests plasma-heavy transfusion improves 30-day survival for patients not requiring massive transfusion.
Risk-Weighted Impact Metric May Reduce Overtreatment of Incidental Aneurysms
A simulation study shows that accounting for the timing of adverse events preserves quality-adjusted life years compared to standard models.
Genetic Diagnosis and Multisuture Fusion Predict Chiari Risk in Lambdoid Synostosis
Longitudinal data suggest routine MRI screening is unnecessary for isolated unilambdoid synostosis but essential for multisuture cases.