Social Rank Modulates Empathic Pain via ACC-NAcC Circuit in Mice
A specific glutamatergic pathway and molecular target influence empathic pain responses based on social hierarchy.
SSRIs Induce Spatially Distinct Molecular Changes in Dorsal Raphe Serotonin Neurons
A mouse study reveals how fluoxetine alters gene expression and neuropeptide levels in specific serotonergic subpopulations.
Postpartum Psychosis Heritability Estimated, Specific Risk Genes Identified
New research quantifies genetic contributions to postpartum psychosis and identifies specific genes, including shared pathways with other psychiatric
Apelin Mediates Exercise's Antidepressant Effects via Hippocampal NMDA Receptors
A muscle-derived protein, apelin, links physical activity to improved mood and neuroplasticity through a specific brain signaling pathway.
Thalamic Connections to Medial Prefrontal Cortex Predict Impulsivity
A new study links specific thalamic subregions, defined by cortical connectivity, to individual differences in delay discounting.
Thalamic-MPFC Connectivity Linked to Individual Differences in Impulsivity
A new study identifies specific thalamic subregions connected to the medial prefrontal cortex as structural correlates of delay discounting.
Nitrous Oxide Addiction Linked to DCN-VTA Circuit, AMPA Receptor Potentiation
A new study identifies how nitrous oxide directly enhances AMPA receptor function in the DCN-VTA circuit, mediating its rewarding effects.
Nitrous Oxide Reward Driven by DCN-VTA Circuit, AMPA Receptor Potentiation
A new study in animal models identifies the specific neural circuit and molecular mechanism underlying nitrous oxide's rewarding effects.
REM Sleep EEG Slowing Linked to Cholinergic Denervation in Older Adults
Specific REM sleep electroencephalogram patterns correlate with brain cholinergic integrity, potentially aiding early diagnosis in Alzheimer's disease
Maternal Fasting in Mice Induces Schizophrenia-Related Phenotypes
A mouse model links transient fasting during early gestation to epigenetic changes and altered neural circuitry in offspring.
Accelerated Deep TMS Protocols Show High Remission Rates in Depression
A randomized trial finds that 10-day accelerated deep TMS protocols achieve 42% to 50% remission rates, exceeding pharmacotherapy alone.
Genetic Risk and Social Deprivation Drive Regional Drug Use Clusters
A Swedish study of 5,983 districts finds that family genetic risk and community deprivation explain most geographic variation in addiction.