Pre-SRS PD-1 Inhibitor Use Linked to Increased Neurological Deficits, Mortality
A multi-institutional study suggests administering PD-1 inhibitors before stereotactic radiosurgery in glioma patients may worsen outcomes.
POD1 Prolactin Levels Predict Long-Term Outcomes After Prolactinoma Resection
Postoperative day 1 prolactin levels help stratify risk for hyperprolactinemia rebound and recurrence, especially with prior dopamine agonist use.
Stereotactic Radiosurgery Improves Tumor Control, Overall Outcomes for Older VS Patients
A retrospective study indicates stereotactic radiosurgery significantly reduces vestibular schwannoma progression and improves neurological outcomes.
Syrinx Shunt Outcomes Vary by Type: Revision Risk vs. Early Neurological Benefit
A retrospective study compares syringopleural, syringosubarachnoid, and syringoperitoneal shunts, detailing revision rates and neurological improvemen
Frontal AVMs Alter fMRI Language Lateralization, Requiring Clinical Caution
A retrospective study indicates that arteriovenous malformations in the frontal lobe significantly affect fMRI-based language lateralization indices.
Occipitotemporal White Matter: Redefining Inferior Longitudinal Fasciculus Components
A combined cadaveric dissection and diffusion tensor imaging study clarifies the anatomical boundaries and subcomponents of key visual and cognitive.
Gamma Knife Surgery Provides Durable Control of Vestibular Schwannoma
A 30-year study shows true tumor progression is rare after 10 years, supporting reduced imaging for patients stable at the 5-year mark.
BRAF V600E Mutation Predicts Early Recurrence in Rathke Cleft Cysts
A retrospective analysis of 383 sellar lesions suggests BRAF-positive cysts behave like papillary craniopharyngiomas and require reclassification.
Transcortical Mapping for Insular Glioma Limits Deficits and Improves Survival
A 500-case analysis identifies specific residual volume thresholds that correlate with survival while keeping permanent deficits under 4%.
Awake Mapping for Grade 2 Glioma Reduces Intractable Epilepsy Burden
Extensive resection of IDH-mutant tumors improves seizure freedom and return-to-work rates, particularly for insular lesions.
Cesium-131 Collagen Tiles Improve Local Control in Recurrent Meningioma
A phase 2 trial shows resection plus brachytherapy achieves 48% local control at five years for aggressive, recurrent meningiomas.
Sublobectomy Extends Survival in IDH-Wildtype Glioblastoma
A retrospective study shows supramaximal resection within functional limits improves survival without increasing neurological deficits.