Taekwondo and Football 5-a-Side Show Highest Injury Risk at Paris Paralympics
Prospective surveillance of 4,450 athletes reveals significant sex-based and sport-specific variations in injury burden and illness rates.
Freezing of Gait Linked to Maladaptive Task Prioritization in Parkinson’s
Patients with freezing of gait maintain walking speed by sacrificing manual task accuracy, driven by impaired theta-band neural activity.
Iron and Lead Levels Linked to Brain Microstructure in Autistic Language Delay
Low serum iron and high lead levels correlate with reduced neurite complexity in language-processing regions of children with autism.
Standard Weight Formulas Overestimate Lung Size in Critically Ill Women
A large-scale analysis reveals that current tidal volume guidelines increase driving pressures and mortality risk for female patients.
Apathy Mechanisms Differ Between Alzheimer's and Parkinson's Disease
Computational modeling reveals distinct effort-sensitivity profiles and neural signatures for motivational loss across neurodegenerative types.
SPAST Variant Mapping Predicts Disease Trajectory in Spastic Paraplegia Type 4
Genetic essentiality mapping and neurofilament levels differentiate rapid functional decline from moderate biphasic progression in SPG4.
Patient Position Alters Quantitative CT Measurements of Interstitial Lung Abnormalities
Supine and prone CT scans show significant variability in lung abnormality quantification, particularly in nonfibrotic components.
Medial Temporal Lesions Impair Memory Precision Rather Than Capacity
Post-surgical data from 40 epilepsy patients show hippocampal damage increases recall variability without reducing the total items retained.
Robotic Pancreatoduodenectomy Increases Hemorrhage Risk Despite Fewer Fistulas
A multicenter study of 1,925 patients finds robotic surgery carries a 63% higher risk of bleeding compared to open procedures.
Cerebral Amyloid Angiopathy Increases Dementia Risk in Memory Clinics
A five-year study of 2,136 patients shows that radiologic markers of amyloid angiopathy predict progression from mild symptoms to dementia.
Sustained Vigorous Activity Linked to Higher Stroke Risk in Hypertensive Adults
Wearable data shows that while moderate activity is protective, vigorous bouts exceeding two minutes may triple stroke risk in hypertension.
Daraxonrasib Shows Activity in Previously Treated RAS-Mutated Pancreatic Cancer
A phase 1-2 study finds that a multiselective RAS inhibitor achieves objective responses and manageable toxicity in advanced disease.