The Briefing
Continuous newsroom coverage of clinically relevant evidence — newest first.
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Seven-Day Low-Plastic Intervention Lowers Urinary Phthalates and Bisphenol A
A randomized trial shows that minimizing plastic contact in food and personal care reduces endocrine disruptors linked to metabolic risk.
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Frailty Scores Influence Steroid Selection but Not Hearing Recovery
A retrospective study of 185 patients shows that while frailty dictates steroid delivery, it does not limit audiometric improvement.
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White Matter Coupling Imbalance Marks Early HIV Neurocognitive Impairment
Structural demyelination and functional reorganization in white matter tracts correlate with clinical status in asymptomatic HIV patients.
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Five-Gene Metabolic Signature Identifies Schizophrenia in Prefrontal Neurons
Researchers identified a diagnostic model based on fatty acid metabolism genes in specific neuronal subtypes with an AUC of 0.856.
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Pseudomonas oryzihabitans Causes Carotid Pseudoaneurysm After Respiratory Infection
A 78-year-old patient developed a life-threatening internal carotid artery lesion three weeks after an untreated common cold.
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Emergency Departments Miss HIV and Syphilis Screening in 88% of STI Cases
A retrospective study of 3,940 patients shows low rates of comprehensive STI testing despite rising national infection rates.
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Sustained Attention Tasks During MRI Improve Prediction of Autistic Traits
Functional imaging during cognitive challenges identifies neural markers of social responsiveness more accurately than resting-state scans.
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Grammatical Boundaries Limit Word Prediction Precision in the Human Brain
Neural responses to word unpredictability decrease at major phrase boundaries, suggesting language processing prioritizes structure over raw statistic
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Clinicians Use Low Platelet Thresholds for Procedures in Refractory Thrombocytopenia
A survey of intensive care practitioners shows many safely place central lines at platelet counts below 20,000/mm3.
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Mediterranean Diet Preserves White Matter Integrity in Hispanic and Latino Adults
Higher adherence correlates with lower white matter hyperintensity volume and better global cognition through cardiovascular health pathways.
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HIT Antibodies Undetectable by ELISA Activate Platelets in Mice and Humans
A prevalent subset of pathogenic antibodies in heparin-induced thrombocytopenia may be missed by standard immunoassays.
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Online Training Increases Fascia Iliaca Block Use for Pediatric Femur Fractures
A web-based module combined with brief hands-on training doubled the rate of ultrasound-guided regional anesthesia in the emergency department.
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Venlafaxine Linked to Probable Induction of De Novo Vocal Tics
A case report identifies the first instance of vocal tics following SNRI use, likely due to fronto-striatal dopamine dysregulation.
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TXA Linked to Lower Reoperation Odds in Posttonsillectomy Hemorrhage
A multicenter study of 19,572 pediatric encounters shows tranexamic acid use increased to 30% by 2024 and reduced reoperation risk by 34%.
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App-Based Cognitive Tasks Increase Subclinical Mental Health Screening Accuracy to 91%
Combining objective neuropsychological metrics with self-reports identifies subclinical distress more accurately than subjective tools alone.
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Severe Childhood Malaria Impairs Cognition Up to 15 Years Later
Ugandan children who survive cerebral malaria or severe malarial anemia show persistent cognitive and math deficits up to 15 years later.
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Thrombectomy Increases Tissue Salvage in Distal Vessel Occlusion Stroke
A post hoc analysis of the DISTAL trial shows endovascular therapy preserves more at-risk brain tissue than medical management alone.
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Interferon-Gamma Drives Chronic Bone Marrow Damage After Doxorubicin in Mice
Targeting T-cell-driven inflammation may prevent long-term skeletal and hematopoietic defects observed in leukemia survivors.
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Algorithm Tracks Patient Signals to Calibrate Psychotherapy Intensity
A four-node framework uses physiological markers and anxiety thresholds to guide real-time clinical decisions and intervention dosing.
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Reduced Loss Aversion and Impaired Response Inhibition Distinguish Suicide Attempters
Cognitive profiling reveals that reduced sensitivity to loss and poor impulse control characterize patients with violent suicide attempts.
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Parenting Styles and Distress Tolerance Mediate Adolescent Self-Injury Risk
A study of 311 adolescents finds that family dynamics and emotional regulation fully mediate the link between impulsivity and self-harm.
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Electroconvulsive Therapy Aids Personality Integration in Adolescent Dissociative Identity Disorder
A case report details how combined neuromodulation and pharmacotherapy resolved three distinct personality states and severe depression.
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Neuropsychiatric Symptoms and CSF Markers Predict General Paresis Outcomes
A 12-month study identifies depression, apathy, and baseline inflammatory markers as key indicators of prognosis in neurosyphilis.
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Revised Chinese DARS Validated for Multidimensional Anhedonia Assessment
A study of 788 psychiatric outpatients confirms a four-factor model for measuring reward deficits across diverse clinical domains.