The Briefing · Psychiatry & Cognitive Neurology
Continuous newsroom coverage of evidence in Psychiatry & Cognitive Neurology — newest first.
Earlier
24 stories-
Transcranial Magnetic Stimulation Reduces PTSD Symptoms in Clinical Cohort
A retrospective study of 127 patients found that 65.4% achieved a clinically meaningful reduction in PCL-5 scores following rTMS treatment.
-
Adolescents at Risk for Bipolar Disorder Show High Self-Harm and Comorbidity Rates
A 12-month study of UK youth finds that those screening positive for bipolar risk receive alternative diagnoses and intensive services.
-
Alzheimer's and Late-Life Depression Show Divergent Molecular Signatures
Structural MRI and cross-modal mapping reveal distinct neurotransmitter and cellular patterns despite overlapping clinical symptoms.
-
Social Stress Drives Sex-Specific Molecular Changes in Female Reward Circuitry
Mouse models and human data reveal that social withdrawal in females involves distinct gene expression patterns in the nucleus accumbens.
-
LB-102 Reduces Acute Schizophrenia Symptoms in Phase 2 Trial
A randomized trial of the benzamide derivative LB-102 demonstrated significant PANSS score improvements across three daily dose levels.
-
Guillain-Barré Syndrome Presents as Catatonic Stupor in Schizophrenia Case
Diminished tendon reflexes and albuminocytologic dissociation distinguish neurologic paralysis from psychiatric immobility.
-
Essential Tremor Patients Retain Empathy Despite Cognitive Decline
A cross-sectional study finds no group-level deficits in empathy or emotional awareness in patients with essential tremor.
-
Baseline Well-Being Predicts Response to Adolescent Emotional Risk Intervention
Adolescents with lower initial quality of life show higher response rates to personalized preventive interventions for emotional disorders.
-
Family Structure Influences Adolescent Depression Risk and Resilience Levels
A study of 29,405 students finds higher depression rates in single-parent and skip-generation households compared to nuclear families.
-
Recent Psychotropic Initiation and Frequent ER Visits Signal Suicide Risk
A nationwide study identifies mood stabilizer initiation and fragmented emergency care as critical proximal markers of suicide risk.
-
DMN Connectivity Predicts Amyloid Accumulation and Clinical Decline in Alzheimer’s
Longitudinal imaging shows functional network disruptions precede detectable amyloid plaques and signal future cognitive impairment.
-
Evidence Accumulation Efficiency Predicts Substance Use Better Than Inhibitory Control
A longitudinal study of 1,000 adults suggests decision-making speed, not impulse suppression, is the primary marker for addiction risk.
-
Dialectical Behavior Therapy and Schema Therapy Show Similar Efficacy for BPD
A 3-year randomized trial found no significant difference in symptom reduction or dropout between these two intensive psychotherapies.
-
Telepractice PTR-F Improves Parent Fidelity in Chinese American Families
A culturally adapted behavioral intervention delivered remotely increased parent adherence and reduced challenging behaviors in autistic children.
-
Clinical and Social Markers Predict Six-Month Alcohol Abstinence
A multivariate analysis of 152 patients identifies treatment completion and organ damage as key indicators of long-term recovery.
-
Quality of Life Buffers Adolescent Risk Behaviors in Configurational Analysis
A study of 560 students identifies specific combinations of depression and alcohol use that drive high-risk clinical profiles.
-
Serum sRAGE Levels Link Biological Rhythm Stability to Depression Severity
A case-control study identifies soluble RAGE as a protective mediator against circadian disruption and insomnia in depressed patients.
-
U-Shaped Sleep Duration Linked to Depression in Postmenopausal Women
Analysis of 4,891 women identifies 7.5 hours as the inflection point where both short and long sleep correlate with symptom severity.
-
Executive Inhibition Deficits Moderate Startle Response in Trauma-Exposed Adults
Poorer cognitive control interacts with physiological hyperarousal to increase the severity of PTSD and depression symptoms over six months.
-
Parental Separation Linked to Increased Mental Disorder Risk in University Students
A large Norwegian survey of 52,968 students finds higher rates of depression, anxiety, and PTSD years after family dissolution.
-
IL-15 Receptor Deficiency Drives Depressive Behaviors via Microglial Synapse Pruning in Mice
Loss of IL-15RA signaling triggers prefrontal cortex synapse loss through the CX3CL1 pathway, offering a potential target for depression.
-
Acetate Supplementation May Reduce Psychotropic-Induced Weight Gain and Dyslipidemia
A case-series shows delayed-release acetate capsules improve metabolic markers and shift gut microbiota toward butyrate-producing bacteria.
-
Behavioral Nursing Model Improves Glycemic Control and Cognition in Older Diabetes Patients
A three-month Information-Motivation-Behavioral Skills intervention reduced HbA1c and psychological distress while improving cognitive scores.
-
Transcriptional Map Identifies 37 Interneuron Subtypes in Human Prefrontal Cortex
Researchers used single-nucleus RNA sequencing to define molecular signatures of somatostatin and parvalbumin cells in healthy adults.