Mailed FIT-DNA Increases Colorectal Cancer Screening Rates in Community Health Centers
A pragmatic trial shows mailed FIT-DNA outreach achieves higher screening uptake than standard FIT, though follow-up colonoscopy rates remain low.
Videolaryngoscopy Increases First-Attempt Success for Double-Lumen Tube Intubation
A multicenter trial of 916 patients shows digital visualization improves glottic view and reduces esophageal intubation rates.
Online Therapist-Assisted Program Reduces Posttraumatic Stress in Injured Children
A randomized trial shows a digital cognitive behavioral intervention lowers symptom scores for six months following pediatric hospitalization.
Repeat OnabotulinumtoxinA for Masseter Prominence Does Not Alter Mandibular Bone
A 12-month placebo-controlled trial using CT imaging shows no significant bone remodeling after masseter injections for facial contouring.
Trabeculectomy Slows Visual Field Loss Better Than Medication in Advanced Glaucoma
A five-year trial shows surgery preserves monocular vision but finds no significant difference in patient-reported quality of life.
Symptom-Based Dosing Reduces Discharge Time in Neonatal Opioid Withdrawal
A cluster randomized trial shows symptom-based dosing shortens medical readiness for discharge when paired with the Eat, Sleep, Console model.
Proximal Nerve Stimulation Improves Sleep Apnea in CPAP-Intolerant Patients
A randomized trial shows proximal hypoglossal nerve stimulation significantly reduces apnea-hypopnea index and daytime sleepiness.
Luvadaxistat Fails to Improve Schizophrenia Cognition in Phase 2 Trial
The ERUDITE study found no significant cognitive benefit from adding the D-amino acid oxidase inhibitor to stable antipsychotic therapy.
Physical Therapy Improves Function More Than CBT in Chronic Low Back Pain
A sequential randomized trial finds physical therapy superior for initial functional gains, though secondary strategies show no difference.
Counterconditioning Stabilizes Neural Safety Signals in PTSD
Functional MRI shows pairing threat stimuli with positive outcomes reinforces safety patterns in the ventromedial prefrontal cortex.
Palliative Telecare Fails to Improve Goal Concordance in Cardiopulmonary Disease
A randomized trial of nurse and social worker-led phone interventions found no change in treatment alignment or patient uncertainty.
Specific RehaCom Modules Predict Processing Speed Gains in Progressive Multiple Sclerosis
Progression in attention-based modules and baseline characteristics like IQ and age determine cognitive outcomes in progressive MS.