Mothers Report Gaps in Prenatal Counseling and Neonatal Realities
A study of 64 mothers finds that 32 percent experienced inconsistencies between antenatal consultations and neonatal intensive care.
Glutamate Receptor Gene Variants Linked to Comorbid ADHD and Autism
Large-scale genomic analysis identifies specific structural variants in glutamatergic networks that distinguish complex ADHD phenotypes.
Sleep and Psychological Symptoms Moderate Physical Activity Benefits in Pediatric Pain
A study of 212,105 adolescents shows that exercise effects on back pain and stomachache depend on comorbid sleep and mood profiles.
Involuntary Prenatal Oxycodone Exposure Increases Addiction Risk in Rat Offspring
A rat study shows that non-contingent maternal opioid use leads to higher motivated drug-seeking in adult progeny than voluntary intake.
Antivirals and Birth-Dose Vaccines Reduce Hepatitis B Transmission and Cancer Risk
Comprehensive management of hepatitis B through early vaccination and targeted antiviral therapy can lower vertical transmission to under 1%.
Antiviral Therapy and Vaccination Strategies Reduce Hepatitis B Mortality
Comprehensive management using serologic markers and antivirals can halve the risk of hepatocellular carcinoma in chronic HBV patients.
Base Editing of Gamma-Globin Promoters Increases Fetal Hemoglobin in Sickle Cell Disease
Interim phase 1-2 data show risto-cel achieves 60% fetal hemoglobin and eliminates severe vaso-occlusive crises in 31 patients.
Black Children Show High Skin Disease Burden but Low Dermatology Use
A multicenter study of 536,776 pediatric patients reveals significant racial gaps in specialty care access for common skin conditions.
Six-Item Symptom Tool and Vestibular Screen Improve Concussion Diagnosis Accuracy
A streamlined 6-item index combined with a brief vestibular-ocular screen shows higher specificity than the standard 22-item checklist.
ECPR May Improve Survival in Pediatric Out-of-Hospital Cardiac Arrest
A multicenter registry study finds higher survival and neurologic recovery rates with extracorporeal support despite wide confidence intervals.
Early Language and Motor Skills Predict Adolescent Independence in Autism
A decade-long longitudinal study identifies preschool markers that determine functional daily living outcomes for autistic teenagers.
Water Access and Vaccination Linked to Lower Pediatric HIV Mortality
Meta-regression of 67 cohorts identifies water access, pneumococcal vaccination, and maternal education as key predictors of survival.