Short-Interval Botulinum Toxin Injections Induce Sustained Glabellar Muscle Suppression
A three-year electromyographic study shows that frequent onabotulinumtoxinA dosing maintains muscle paralysis 48 weeks after treatment ends.
Immersive Virtual Reality Improves Naming in Chronic Non-Fluent Aphasia
A randomized trial shows immersive therapy yields higher gains in oral motor function and patient enjoyment than conventional methods.
Age, Rhythm, and Low-Flow Duration Predict Neurological Recovery After ECPR
A 14-year cohort study identifies specific predictors to help clinicians select cardiac arrest patients for extracorporeal resuscitation.
GABAA Gain-of-Function Mutation Triggers Seizures via Interneuron Network Collapse in Mice
A study of the GABRB3 p.(Glu77Lys) variant reveals how enhanced inhibitory signaling paradoxically drives cortical hyperexcitability.
Preoperative Beta Connectivity Predicts Delirium Risk in Older Surgical Patients
A multicenter study finds reduced brain network communication at baseline identifies vulnerability, though EEG patterns recover by 3 months.
Genetic Factors Drive Association Between Infections and Tic Disorder Risk
A Swedish cohort study of 3.8 million people suggests shared genetic pleiotropy links infection history to Tourette syndrome risk.
Telehealth Interdisciplinary Care Reduces Symptoms in Persistent Post-Concussion Syndrome
A single-case experimental study shows remote delivery of multi-modal rehabilitation improves functional goals and symptom severity.
Childhood Cognitive Control Predicts Adult Tic Remission and Income
Early executive function measures in children with Tourette syndrome correlate with clinical and socioeconomic success 11 years later.
Standard Activity Guidelines Better Preserve Hippocampal Volume Than HIIT in Older Adults
A nine-year study finds that baseline fitness and moderate activity provide more durable neuroprotection than high-intensity training.
Eleven-Protein Plasma Panel Identifies Parkinson’s Disease Across Four Cohorts
A machine learning model using 11 plasma proteins differentiated Parkinson’s from other neurological conditions with high accuracy.
Hypothalamic Astrocytes Drive Dexmedetomidine Sedation via Calcium Signaling in Mice
Researchers identified a specific astrocytic pathway that modulates inhibitory GABA currents to facilitate pharmacological sedation.
Bedside AI Analyzes EEG to Predict Cardiac Arrest Outcomes
A deep learning tool integrated into ICU monitors provides continuous prognostic trajectories for comatose patients within 36 hours.