CGRP Inhibitors Reduce Glaucoma Risk Compared to Traditional Migraine Preventives
A large cohort study finds monoclonal antibody CGRP inhibitors lower incident glaucoma risk by 25% over three years.
Deep Learning Automates PET RANO Criteria Extraction in Glioma Imaging
An externally validated model achieves high agreement with experts in quantifying metabolic tumor volume and tumor-to-background ratios.
Pure Autonomic Failure Carries 5% Annual Risk of Central Phenoconversion
A meta-analysis identifies hyposmia and sleep disturbances as key predictors of progression to Parkinson disease or multiple system atrophy.
Heartbeat Evoked Potential Lacks Consistency for Clinical Use
A meta-analysis finds that methodological variability prevents using this neural marker of interoception as a reliable diagnostic tool.
US Neurology Wait Times Average 50 Days Following Primary Care Referral
A retrospective analysis of 114,034 patients identifies significant delays for multiple sclerosis and regional disparities in access.
24-Hour Blood Pressure Variability Linked to Cognitive Decline and Brain Aging
Fluctuations in ambulatory blood pressure correlate with impaired executive function and blood-brain barrier leakage in older adults.
Cutaneous pTDP-43 Deposits Distinguish ALS From Other Neuropathies
Skin and tongue biopsies detect phosphorylated TDP-43 pathology that correlates with clinical disease stage in patients with ALS.
Forefoot MRI Pacinian Corpuscle Count Correlates With Diabetic Neuropathy Severity
Loss of mechanoreceptors on routine imaging mirrors electrophysiological deficits in large-fiber sensory dysfunction.
Status Epilepticus Mortality Rises in the United States Since 2007
A 22-year analysis of CDC data reveals increasing death rates and significant racial and regional disparities in status epilepticus.
Telehealth Hypnotic Cognitive Therapy Reduces Chronic Pain After Spinal Cord Injury
A randomized trial demonstrates that remote delivery of hypnotic cognitive therapy significantly lowers pain intensity and depression.
Post-Thrombectomy Blood Pressure Drops Linked to Increased Disability
Systolic decreases of 40 mm Hg or more within 24 hours of successful recanalization correlate with worse functional recovery.
Triglyceride-Glucose Index Linked to Cognitive Deficits in Depression and Diabetes
A high triglyceride-glucose index correlates with cognitive impairment via inflammatory and tau-related pathways in comorbid patients.