Postoperative Forehead Elongation Linked to Frontalis Relaxation Not Tissue Migration
Analysis of 35 patients using AI landmark detection shows forehead height remains stable when frontalis contraction is eliminated.
Erythroid FGF23 Directly Inhibits Red Cell Production in Mouse Models
Local fibroblast growth factor 23 signaling in the bone marrow impairs erythropoiesis through FGFR1 activation and mitochondrial dysfunction.
Mosunetuzumab and Polatuzumab Vedotin Show High Response in Refractory MCL
A phase 2 trial reports a 78.6% complete response rate in patients with mantle cell lymphoma after Bruton tyrosine kinase inhibitor failure.
Childhood Cognitive Control Predicts Adult Tic Remission and Income
Early executive function measures in children with Tourette syndrome correlate with clinical and socioeconomic success 11 years later.
LDTM Transfer Achieves 91% Return-to-Work Rate for Subscapularis Tears
A retrospective study of 189 patients shows significant functional gains and a mean five-month return to employment after tendon transfer.
Standard Activity Guidelines Better Preserve Hippocampal Volume Than HIIT in Older Adults
A nine-year study finds that baseline fitness and moderate activity provide more durable neuroprotection than high-intensity training.
Eleven-Protein Plasma Panel Identifies Parkinson’s Disease Across Four Cohorts
A machine learning model using 11 plasma proteins differentiated Parkinson’s from other neurological conditions with high accuracy.
Hypothalamic Astrocytes Drive Dexmedetomidine Sedation via Calcium Signaling in Mice
Researchers identified a specific astrocytic pathway that modulates inhibitory GABA currents to facilitate pharmacological sedation.
Activity Modality and Social Context Alter Pediatric Brain Structure
A longitudinal study of 8,230 children links physical-social engagement to increased frontoparietal volume and lower psychiatric risk.
Prenatal Sterol-Inhibiting Drugs Linked to Increased Autism Risk
A study of 6 million births found that common medications disrupting cholesterol synthesis increase autism risk in a dose-dependent manner.
Dexmedetomidine Linked to Lower Mortality in ICU Patients With Delirium
A retrospective analysis of two large databases shows reduced in-hospital and one-year mortality for delirious patients given the sedative.
Subanesthetic Ketamine Improves Depressive Symptoms in Critically Ill Adults
A retrospective study finds three days of low-dose ketamine reduces sadness in ICU patients with minimal hemodynamic impact.