SSPOP Gene Mutations Linked to Pediatric Epilepsy and Developmental Delay
Researchers identify pathogenic variants in a presumed pseudogene, expanding the diagnostic landscape for unexplained seizure disorders.
Prostate SBRT Maintains 90% Relapse-Free Survival at Ten Years
A multi-center trial of 310 patients shows low- and intermediate-risk prostate cancer control remains durable with minimal late toxicity.
CT Metrics Predict Benralizumab Response in Severe Asthma
Quantitative imaging of small airway disease and sinus opacification identifies responders more accurately than blood eosinophil counts.
Magnetic Seizure Therapy Limits Memory Loss in Bipolar Depression Trial
A randomized pilot study shows magnetic seizure therapy matches the efficacy of ultrabrief ECT while reducing cognitive adverse effects.
Microsurgical Breast Reconstruction Remains Undervalued Despite Improved Efficiency
A 13-year analysis reveals that while free flap reimbursement per hour has risen, it still lags significantly behind implant-based options.
Skin Biopsies Differentiate Body-First and Brain-First Parkinson’s Disease
Cutaneous alpha-synuclein patterns and seeding kinetics identify distinct pathological origins in Parkinson’s disease subtypes.
Prefrontal Cortex Origin for Rhythmic Ictal Nonclonic Hand Motions
Intracerebral recordings show that specific hand motions often linked to temporal lobe epilepsy can originate in the middle frontal gyrus.
Automated Software Identifies Hundreds of Patients Lost to Aneurysm Follow-Up
Natural language processing of 7.5 million imaging reports captured 492 new patients and generated 47 surgical repairs.
Brain FAAH Levels Rise During Short-Term Cannabis Abstinence
PET imaging shows enzyme increases in the ventral striatum correlate with depression and impulsivity during early withdrawal.
Perinatal Cash Transfers Linked to 32% Drop in Infant Maltreatment Reports
A study of Flint's Rx Kids program shows unconditional cash support significantly reduces child protective services investigations.
Transcortical Mapping for Insular Glioma Limits Deficits and Improves Survival
A 500-case analysis identifies specific residual volume thresholds that correlate with survival while keeping permanent deficits under 4%.
Advanced Paternal Age Increases Autism Risk in Grandchildren via Female Lineage
A registry study of 12.6 million people shows that a grandfather's age at his daughter's birth influences his grandchildren's autism risk.