MIPD Improves Early Postoperative Activity, Reduces Stress for Pancreatic Resection
A randomized trial shows minimally invasive pancreatoduodenectomy leads to higher physical activity and heart rate variability for weeks.
IL-6 Inhibition Shows Clinical Signals in Refractory Depression
A small trial of tocilizumab for difficult-to-treat depression suggests potential for symptom improvement and identifies patient selection markers.
Diabetes Worsens Bronchiectasis Outcomes, Increases Comorbidities and Infection Risk
A large registry analysis confirms diabetes significantly impacts disease severity, exacerbations, hospitalizations, and mortality in bronchiectasis.
Buried DIEP Flaps Show Similar Complication Rates to Skin Paddle Flaps
A retrospective review suggests completely burying deep inferior epigastric perforator flaps does not increase overall complication rates.
Anhedonia Severity Predicts Intermittent Theta-Burst Stimulation Response in MDD
Baseline anhedonia levels influence neurophysiological and clinical outcomes following iTBS for major depressive disorder.
Nasal Septal Perforation Impairs Olfactory and Trigeminal Function
A cross-sectional study links larger perforation areas and higher BMI to worse olfactory identification in patients with NSP.
Subsolid Lung Nodules Show High 5-Year Survival, Low Nodule-Related Mortality
A large cohort study clarifies the natural history and long-term outcomes of subsolid and ground-glass lung nodules.
Weight Loss Intervention Safe in Older AF Patients, But Does Not Improve Symptoms
A randomized clinical trial indicates that while weight loss is achievable and safe in older, overweight AF patients, it may not reduce AF symptoms.
Individual LPFC Maps Reveal Fine-Grained, Interdigitated Networks
Precision fMRI in 10 individuals shows the lateral prefrontal cortex has a more fragmented and functionally distinct organization than group.
MIF Modulates Astrocyte Distribution in Schizophrenia Cortical Spheroids
A new study using patient-derived brain models identifies macrophage migration inhibitory factor (MIF) as a key regulator of astrocyte function.
Azithromycin Does Not Reduce Acute Wheezing Severity in Preschoolers
A multicenter trial found azithromycin offered no significant clinical benefit over placebo for moderate-to-severe wheezing symptoms.
Melittin Mitigates Doxorubicin-Induced Neurotoxicity in Murine Models
A study in mice suggests melittin, a bee venom component, reduces doxorubicin's neurotoxic effects by targeting inflammation and oxidative stress.