Serious Games Reduce Geriatric Trauma Undertriage in Nontrauma Centers
A randomized trial of 800 emergency physicians shows digital simulation training improves adherence to triage guidelines for older adults.
TTVR Eliminates Severe Tricuspid Regurgitation in Real-World Registry
A US registry study of 1,034 patients shows 98% procedural success and significant functional gains with low 30-day mortality.
Preconception Care Reduces Maternal and Neonatal Morbidity
A review highlights evidence-based interventions, from folic acid to chronic disease management, that optimize health before conception.
Rapid Susceptibility Testing Speeds Antibiotic Adjustments but Not Outcomes
While rapid testing accelerated antibiotic adjustments by 14 hours, it did not improve 30-day survival or reduce deleterious events.
US Adult Obesity Projected to Reach 47 Percent by 2035
An analysis of over 11 million adults reveals severe racial and geographic disparities as obesity rates continue to climb nationwide.
Caffeinated Coffee and Tea Lower Dementia Risk; Decaf Shows No Benefit
A 43-year prospective study of 131,821 adults reveals that 2 to 3 cups of caffeinated coffee daily significantly reduces incident dementia.
Opioid Medications Halve Mortality but Reach Only a Quarter of Patients
A clinical review details how optimizing methadone, buprenorphine, and naloxone can close the treatment gap and reduce all-cause mortality.
Tumor Debulking Adds Toxicity Without Survival Benefit in Metastatic Colorectal Cancer
Adding tumor debulking to chemotherapy fails to extend survival and increases severe adverse events in metastatic colorectal cancer.
Limiting ICU Wrist Restraints Fails to Increase Delirium-Free Days
A restrictive wrist-strap protocol in mechanically ventilated adults did not improve delirium-free days or increase self-extubation risk.
Structured Diagnostic Approach Guides Management of Chronic Diarrhea
A comprehensive clinical review details specific red flags for endoscopic evaluation and outlines empiric therapies that improve symptoms.
Decision Tool Reduces Antidepressant Discontinuation in Depression
A web-based system personalizing antidepressant selection kept more patients on therapy at 8 weeks and improved symptoms at 24 weeks.
Greater Than 10% Weight Loss Needed to Reduce Obesity-Linked Cancers
Observational data show bariatric surgery or GLP-1 agonists yield modest absolute risk reductions of 0.02% to 0.5% in cancer incidence.