Retinal Imaging AI Screens for Six Systemic Metabolic and Endocrine Diseases
A multitask framework identifies diabetes, hypertension, and osteoporosis from fundus photos, showing high negative predictive value in primary care.
Spectral CT Reconstructions Improve Acute Bowel Ischemia Detection
Adding iodine maps and monoenergetic images to portal venous CT increases diagnostic accuracy from 73% to 86% across scanner platforms.
Ultrasound-Derived Fat Fraction Accurately Grades Steatosis in Chronic Liver Disease
A multicenter study shows ultrasound-derived fat fraction provides high diagnostic accuracy across diverse etiologies and fibrosis stages.
Artificial Intelligence Matches Physician Committees in Adjudicating Cardiovascular Trial Endpoints
An automated system shows high agreement with human experts in identifying major adverse cardiovascular events in a large clinical trial.
Explainable AI Identifies Cortical Asymmetry to Detect Major Depression
A deep learning model using fNIRS data achieves 81% accuracy by mapping hemodynamic imbalances in the dorsolateral prefrontal cortex.
Photon-Counting CT Matches V/Q SPECT for CTEPH Perfusion Mapping
A retrospective study shows high quantitative concordance between photon-counting CT and scintigraphy for lobar lung perfusion assessment.
Normalization Choice Impacts Molecular Rejection Diagnosis in Kidney Transplants
Standardized data processing maintains high diagnostic accuracy for antibody and T cell-mediated rejection in allograft biopsies.
Training-Free AI Framework Automates Radiographic Morphometry Across Multiple Joints
A generalist landmark matching model achieves measurement accuracy comparable to radiologists without requiring anatomy-specific datasets.
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[89Zr]girentuximab PET Identifies Any Renal Malignancy with 98% Positive Predictive Value
A secondary analysis of the ZIRCON trial indicates the CAIX-targeted tracer detects non-clear cell subtypes with high clinical accuracy.
Imaging Accurately Stages Nodal Squamous Cell Carcinoma Except in Immunosuppression
Ultrasonography and CT show 100% sensitivity in immunocompetent patients but fail to detect most early metastases in the immunosuppressed.
Contrast-Enhanced MRI Improves Mesorectal Nodal Staging Accuracy in Rectal Cancer
The Avocado Sign on T1-weighted imaging shows higher sensitivity and specificity than standard T2-weighted morphological criteria.
Breath Analysis Distinguishes Alzheimer’s Disease From Other Dementias
A diagnostic model using exhaled volatile organic compounds identifies Alzheimer’s disease with 93% accuracy in a 241-patient cohort.