Comorbidities and Technique Drive International Differences in BPA Outcomes
A multicenter study finds that occult cardiopulmonary factors and balloon size explain higher residual pressures after pulmonary angioplasty.
Low Cerebral Perfusion Pressure Increases Delirium Risk After Cardiac Surgery
A cohort study of 1,759 patients suggests that maintaining the balance between arterial and venous pressures may prevent delirium.
Hybrid Deep Learning Model Predicts 24-Hour Sepsis Mortality Using Treatment Response
A lightweight architecture integrating vasopressor titration and urine output achieves high negative predictive value for short-term risk.
Manual Pressure Augmentation During Defibrillation Does Not Improve Survival
A randomized trial found that while manual pressure reduces transthoracic impedance, it does not increase survival to hospital discharge.
Next-Generation Troponin T Assay Reduces Myocardial Injury Classification
The sixth-generation assay maintains diagnostic accuracy while identifying fewer patients with elevated levels above the reference limit.
ECPR May Improve Survival in Pediatric Out-of-Hospital Cardiac Arrest
A multicenter registry study finds higher survival and neurologic recovery rates with extracorporeal support despite wide confidence intervals.
Restrictive Sepsis Resuscitation Shows No Long-Term Functional Deficits
A randomized trial finds similar cognitive and physical outcomes at 12 months for restrictive versus liberal fluid strategies in sepsis.
Non-Intubated ECMO Failure Linked to Seven-Fold Increase in 90-Day Mortality
An international cohort study finds that while avoiding mechanical ventilation during ECMO is feasible, failure carries high mortality risks.
Multiarm Platform Evaluates Traumatic Wound Care During War in Ukraine
Researchers implement a multistage protocol to test devices and therapies for infected wounds amid rising antimicrobial resistance.
Troponin I to T Ratio Distinguishes Acute Necrosis From Chronic Injury
A multicohort study finds the troponin ratio identifies lethal cell death and improves differentiation of type 1 and 2 myocardial infarction.
Elective Microaxial Flow Pump Does Not Improve High-Risk PCI Outcomes
A randomized trial finds no clinical benefit and a potential mortality signal with routine mechanical unloading during complex revascularization.
Microaxial Flow Pump Fails to Improve Outcomes in High-Risk PCI
A randomized trial of 300 patients shows elective left ventricular unloading does not reduce major adverse events at 12 months.