Balanced Fluids and Saline Show Similar Outcomes in Pediatric Septic Shock
A large trial of over 8,000 children found no difference in kidney events or mortality between balanced crystalloids and 0.9% saline.
Early Thrombectomy Reduces Intubation Risk in Pulmonary Embolism
Intervention within 12 hours of diagnosis improves hemodynamic recovery and lowers respiratory failure rates in intermediate-risk patients.
Cardiac Arrest Increases Mortality and Coronary Complexity in STEMI Shock
A retrospective study of 345 patients shows that cardiac arrest in cardiogenic shock signals higher SYNTAX scores and 80% 1-year mortality.
Early Thrombectomy Reduces Intubation in Intermediate-Risk Pulmonary Embolism
Intervention within 12 hours improves hemodynamic recovery and lowers ventilation risk despite similar mortality to delayed procedures.
Remote Ischaemic Preconditioning Fails to Prevent Postoperative Myocardial Injury
A randomized trial of two-session preconditioning in abdominal surgery shows no reduction in injury and a paradoxical troponin increase.
Daily Resistance Training and Verticalization Safe During ECMO Support
A pilot study shows that structured mobility and resistance exercises correlate with improved functional performance in critically ill adults.
Structured Exercise and Resistance Training Safe During ECMO Support
A pilot study of 20 patients shows that intensive twice-daily rehabilitation correlates with improved functional performance and survival.
Ketamine Does Not Reduce 28-Day Mortality Compared With Etomidate
A randomized trial of 2,365 critically ill adults found no survival benefit for ketamine, despite a higher rate of cardiovascular collapse.
Early Plasma Reduces Mortality in Traumatic Intracranial Hemorrhage
A retrospective study of 6,183 patients shows a 5% absolute survival drop for every 10-minute delay in plasma during the first half hour.
Indirect Expenses Account for 86 Percent of Trauma Resuscitation Costs
A time-driven activity-based costing analysis of 134 patients shows the average 17-minute resuscitation costs $3,628.
RRT Configuration Does Not Impact Complication Rates in VA-ECMO Patients
A retrospective study finds no significant differences in infection or bleeding between integrated and parallel renal replacement circuits.
Low Diaphragm Thickening Fraction at One Hour Predicts Noninvasive Ventilation Failure
Bedside ultrasound of the diaphragm after 60 minutes of support identifies patients likely to require endotracheal intubation.