Absence of Chest Pain Predicts Severe Pediatric Myocarditis Risk
A retrospective study identifies hemodynamic instability and elevated procalcitonin as key markers for ICU admission in children.
Continuous Probabilities Identify High-Risk Patients in Hypoinflammatory Respiratory Failure
Continuous modeling of IL-6 and sTNFR-1 reveals a 40% mortality risk in patients masked by binary inflammatory classification.
Low MicroRNA-362 Linked to Acute Lung Injury After Murine Brain Trauma
Downregulation of microRNA-362-3' in extracellular vesicles fails to suppress proinflammatory TIMP-1 in a mouse model of head injury.
Non-Invasive Tools Estimate Intracranial Pressure When Invasive Monitoring Is Contraindicated
A review evaluates ultrasound and imaging techniques to detect intracranial hypertension in patients with coagulopathy or liver failure.
Videolaryngoscopy Increases First-Attempt Success for Double-Lumen Tube Intubation
A multicenter trial of 916 patients shows digital visualization improves glottic view and reduces esophageal intubation rates.
Serum Neurofilament Light Chain Tracks Acute Injury in Refractory Status Epilepticus
Elevated NfL levels distinguish cryptogenic NORSE from other seizure etiologies and correlate with poor functional outcomes at discharge.
Heterogeneous Trial Endpoints Limit Evidence in Acute Kidney Injury
A review of 251 trials reveals inconsistent outcome definitions and measurements that hinder clinical application of renal research.
Hemothorax Volume Under 300 mL Predicts Successful Observation
A multicenter study finds that traumatic hemothorax volume over 300 mL increases the risk of observation failure sixteenfold.
Resuscitative Thoracotomy Yields 7.4 Percent Survival in Combat Trauma
A retrospective cohort study shows survival rates comparable to civilian trauma despite high-energy blast injuries and severe hemorrhage.
Auricular Vagus Nerve Stimulation Manages Refractory Sympathetic Hyperactivity Post-Hemorrhage
Adjunctive neuromodulation improved tachypnea and consciousness while reducing polypharmacy in a patient with intracerebral hemorrhage.
High-Ratio Plasma Resuscitation Reduces Mortality in Moderate Traumatic Brain Injury
A large database analysis suggests plasma-heavy transfusion improves 30-day survival for patients not requiring massive transfusion.
Donor Factors and Platelet Degranulation Drive Whole Blood Antifibrinolytic Variability
A study of 28 whole blood units identifies distinct high and low PAI-1 activity cohorts linked to endothelial markers and storage lesions.