Standardized Protocol Alters Medication Use in Pediatric Cannabis Hyperemesis Syndrome
Implementation of a clinical pathway increased capsaicin and metoclopramide use while reducing haloperidol dosages in adolescents.
Clinical Pathway Reduces Pediatric CT Use to 22 Percent
A multidisciplinary protocol met national quality benchmarks while cutting emergency department wait times by over 100 minutes.
Picloram Exposure Increases Early-Onset Colorectal Cancer Risk in Epigenetic Analysis
Methylation risk scores identify the herbicide picloram as a significant driver of colorectal cancer in patients under age 50.
Paramedic Patella Reduction Reduces Hospital Transport and Dislocation Time
A retrospective analysis of 1,210 patients shows a 91.8% success rate for prehospital reduction, cutting dislocation time by 71 minutes.
Short-Interval Botulinum Toxin Injections Induce Sustained Glabellar Muscle Suppression
A three-year electromyographic study shows that frequent onabotulinumtoxinA dosing maintains muscle paralysis 48 weeks after treatment ends.
Metabolic Disease Burden Rises in Southern Italy Despite National Declines
A 33-year analysis reveals widening geographic disparities in metabolic health and a growing proportion of unattributable disease burden.
Age, Rhythm, and Low-Flow Duration Predict Neurological Recovery After ECPR
A 14-year cohort study identifies specific predictors to help clinicians select cardiac arrest patients for extracorporeal resuscitation.
Three or More Breast Cancer Foci Increase Specific Mortality Risk
A Swedish cohort study of 71,607 women finds that multifocality independently predicts worse survival despite traditional staging.
School Transition Drives Adolescent Well-being Decline More Than Aging
A longitudinal study of 20,910 students shows secondary school transition triggers well-being deficits lasting over two years.
French Cohort Study Maps Perinatal Risks for Neurodevelopmental Disorders
A study of 7.4 million children identifies shared and distinct risk factors for ADHD, autism, and intellectual disability.
Endothelial Expansion Drives Vascular Hyalinization in Castleman Disease
Transcriptomic analysis identifies endothelial-B cell crosstalk as a primary driver of stromal dysregulation and systemic inflammation.
Cystatin C Discrepancy Predicts Kidney Injury and Death in Cell Therapy
A 30% gap between creatinine and cystatin C filtration estimates identifies high-risk transplant and T-cell therapy candidates.