Continuous EEG Enhances Detection of Post-Stroke Epilepsy Predictors
A retrospective study shows continuous EEG significantly improves identification of epileptiform activity and prediction of post-stroke epilepsy.
Cingulum Hippocampus White Matter Integrity Linked to Suicide Attempts in Bipolar Disorder
Reduced fractional anisotropy in the cingulum hippocampus, mediated by impulsivity, associates with suicide attempts in bipolar disorder.
Accelerometer Data Predicts Dementia Risk in Older Adults
Objective sleep-wake cycle metrics from wearables modestly enhance dementia risk prediction, comparable to APOE genotype.
AA and SNMMI launch 2025 guideline for Amyloid and Tau PET Appropriate Use Criteria
New guidelines expand appropriate use of amyloid and tau PET, particularly for eligibility and monitoring of amyloid-targeting therapies.
Alzheimer's Association launches 2024 guideline for Alzheimer's disease and related dementias
New guidance empowers primary care clinicians with a structured, patient-centered approach to diagnostic evaluation, testing, counseling.
Syrinx Shunt Outcomes Vary by Type: Revision Risk vs. Early Neurological Benefit
A retrospective study compares syringopleural, syringosubarachnoid, and syringoperitoneal shunts, detailing revision rates and neurological improvemen
Tea Polyphenols Mitigate Brain Changes, Anxiety in Aged Diabetic Rats
A preclinical study in aged T2DM rats suggests tea polyphenol intervention may improve hippocampal structure, function, and behavior.
Diffuse White Matter Abnormalities Do Not Predict Long-Term Dementia Risk
A 10-year study finds that 'dirty-appearing' white matter lacks the prognostic weight of focal hyperintensities in older adults.
Lamotrigine-Topiramate Duotherapy Increases Congenital Malformation Risk Fourfold
A large registry study identifies a significant risk increase for specific antiseizure drug combinations used during the first trimester.
Biallelic EIPR1 Variants Cause Neurodevelopmental Syndrome and Neutropenia
Defects in endosomal recycling and dense core vesicle biogenesis drive a spectrum of microcephaly, ataxia, and spasticity.
Frontal AVMs Alter fMRI Language Lateralization, Requiring Clinical Caution
A retrospective study indicates that arteriovenous malformations in the frontal lobe significantly affect fMRI-based language lateralization indices.
Cutamesine Mitigates Hippocampal Damage in In Vitro Ischemia Models
A sigma-1 receptor agonist reduced neuronal cell death and cellular stress markers in rat hippocampal slices exposed to oxygen-glucose deprivation.