Higher Daily Step Counts Linked to Reduced Bradykinesia and Increased Dyskinesia
Objective wearable data from 80 patients shows a correlation between physical activity and motor symptom trade-offs in Parkinson's disease.
Schizophrenia Subtype Shows Low Striatal Dopamine and Iron Accumulation
A frontotemporal dementia-like phenotype in schizophrenia patients challenges the universal hyperdopaminergic model of the disease.
Brain-Responsive Neurostimulation Reduces Focal Seizures by 82% at Three Years
A prospective real-world study shows higher seizure reduction rates and lower SUDEP risk than observed in initial clinical trials.
Auricular Vagus Nerve Stimulation Manages Refractory Sympathetic Hyperactivity Post-Hemorrhage
Adjunctive neuromodulation improved tachypnea and consciousness while reducing polypharmacy in a patient with intracerebral hemorrhage.
Epilepsy Patients Show Amyloid-Independent Tau Deposition Linked to Clinical Severity
PET imaging and proteomics reveal that chronic epilepsy correlates with widespread tau accumulation and accelerated multi-organ aging.
High-Ratio Plasma Resuscitation Reduces Mortality in Moderate Traumatic Brain Injury
A large database analysis suggests plasma-heavy transfusion improves 30-day survival for patients not requiring massive transfusion.
Optimal Sleep Duration Mitigates Five-Fold Dementia Risk in Focal Epilepsy
A UK Biobank study finds 6 to 8 hours of sleep significantly preserves executive function and reduces dementia risk in epilepsy patients.
Chronic Back Pain Linked to Sensory Cortex Hyperactivity During Walking
Patients with nonspecific low back pain show increased neural load in somatosensory regions and reduced gait velocity during dual tasks.
CSF Outflow Resistance and Callosal Angle Predict iNPH Shunt Outcomes
Elevated fluid resistance and preserved preoperative cognition correlate with sustained functional gains after ventriculoperitoneal shunting.
Blood MicroRNA Signatures Correlate With Hippocampal Volume and Atrophy Rates
Specific microRNA expression patterns in whole blood may serve as early markers for structural brain changes and neurodegenerative risk.
Deep Learning Synthesizes Contrast-Enhanced CT and MRI Scans
A scoping review of 56 studies shows high image fidelity but limited evidence for diagnostic interchangeability in clinical practice.
Peritruncal Blood Volume Predicts Shunt Dependency and Functional Recovery in aSAH
Infratentorial hematoma volume shows stronger associations with long-term outcomes than traditional Fisher scales in subarachnoid hemorrhage.