Breast GPA Predicts Intracranial Progression and Survival in Breast Cancer
A large cohort study links local brain control to overall survival, identifying tumor subtype and performance status as key predictors.
Neurosurgeons Disagree on Resectability in Recurrent Glioblastoma Trial
A post-hoc analysis reveals low inter-rater agreement on surgical feasibility and no link between surgeon consensus and survival.
Early Radiographic Response Poorly Predicts Local Control in Brain Metastases
A large cohort study finds that stable disease and partial response carry similar recurrence risks after radiation therapy.
CHK1 Inhibition Sensitizes Experimental Glioma to CDK4/6 Blockade
CRISPR screening identifies AMBRA1 and CCNE1 as drivers of resistance while suggesting dual CHK1 and CDK4/6 targeting as a viable strategy.
Deep Learning Automates PET RANO Criteria Extraction in Glioma Imaging
An externally validated model achieves high agreement with experts in quantifying metabolic tumor volume and tumor-to-background ratios.
AI Model Predicts Glioblastoma Infiltration Beyond Visible Tumor Margins
A prospective trial validates an AI tool using biopsies to map microscopic tumor spread and predict survival in glioblastoma patients.
Coping and Self-Efficacy Mediate Mood Improvements in Brain Tumor Caregivers
A secondary analysis of a randomized trial shows that a telehealth intervention reduces anxiety and depression by targeting specific psychological mec