Brain
Mixed-Methods Study
4-Hydroxybenzoic Acid Restores Endogenous Coenzyme Q10 in COQ2-Deficient Patient
A first-in-human trial shows 4-HBA bypasses biosynthetic blocks to improve neurological and renal outcomes in primary CoQ10 deficiency.
Brain
Mixed-Methods Study
Nuclear Membrane Disruption Precedes Cytoplasmic Tau in Anti-IgLON5 Disease
Autopsy and in vitro data show that antibody binding triggers nuclear invaginations and serine 422 phosphorylation before tau aggregates.
Brain
Mixed-Methods Study
Identical EEG Bursts Signal Severe Loss of Brain Network Complexity
A multi-model study identifies identical burst suppression as a default state of simplified excitatory networks in irreversible coma.
British Journal of Sports Medicine
Mixed-Methods Study
FIFA Decision Aid Standardizes Pregnancy Management in Football
A validated five-step framework helps multidisciplinary teams assess risks and support informed participation for pregnant athletes.
Pediatrics
Mixed-Methods Study
Children's Hospitals Delay Effective Surge Strategies Despite Tracking Occupancy
A national study shows a disconnect between capacity metrics and the operational triggers used to mitigate inpatient strain.