Ceruloplasmin Deficiency Linked to Fusiform Gyrus Pathology in Autism Subtype
Low ceruloplasmin levels drive lipid and myelin imbalances in children with autism and atypical visual processing.
Apixaban Reduces Recurrent Stroke in Patients Without High-Risk Hypertension
An ARCADIA trial analysis shows apixaban is more effective than aspirin only when severe hypertension and cardiac hypertrophy are absent.
Hodgkin Lymphoma Survivors Face Quality of Life Deficits Decades After Diagnosis
A nationwide study shows persistent fatigue and dyspnea in survivors compared to the general population, even 10 years post-treatment.
EEG Topological Mapping Distinguishes Mild from Moderate Stroke with 86% Accuracy
Persistent homology identifies higher-order network disruptions in the prefrontal cortex to improve objective stroke severity assessment.
Cibisatamab and FAP-4-1BBL Show Activity in Refractory Colorectal Cancer
A phase 1b trial finds that combining a CEA-targeted bispecific antibody with localized 4-1BB co-stimulation induces objective responses.
Cannabis Use Blunts Neurocognitive Development in Adolescents
Longitudinal data and hair toxicology link THC exposure to flattened growth in memory and processing speed from ages 9 to 17.
One in Four Non-Comatose Cardiac Arrest Survivors Face Poor Outcomes
A registry analysis identifies age, motor response, and pH levels as key predictors of 30-day recovery in patients who avoid post-arrest coma.
Increased Tibial Slope Raises Risk of Meniscal Allograft Failure
A retrospective cohort study finds higher posterior tibial slope correlates with reoperation and failure despite stable functional scores.
Systematic Review Evaluates 70 Years of Neuroimaging in Extra-Sensory Perception
Analysis of 143 reports identifies potential electrophysiological markers despite widespread methodological limitations and small samples.
Gut Permeability Triggers Atrial Fibrillation via JNK2 Activation in Mice
Intestinal barrier dysfunction releases cytokines that activate cardiac JNK2, driving the calcium leaks that sustain atrial arrhythmias.
Lower Tau PET Sensitivity in Older Men Reflects Reduced Tangle Density
Flortaucipir PET sensitivity for advanced Alzheimer pathology drops to 42% in patients over 83, mirroring lower biological tangle burdens.
Coronary CT Angiography Misses Over One Third of Calcified Plaques
High-resolution non-contrast CT identifies small, low-density calcifications overlooked by standard angiography in nearly 9% of patients.