Continuous EEG Enhances Detection of Post-Stroke Epilepsy Predictors
A retrospective study shows continuous EEG significantly improves identification of epileptiform activity and prediction of post-stroke epilepsy.
Nebulized Heparin Linked to Reduced Mortality, More Ventilation-Free Days in Respiratory Failure
A meta-analysis suggests nebulized unfractionated heparin improves survival and ventilation-free days in adults with acute respiratory failure…
Armchair Positioning Improves Oxygenation in Spontaneously Breathing ICU Patients
A randomized controlled trial found out-of-bed armchair positioning increased PaO2/FiO2 ratios compared to in-bed semi-recumbent positioning.
LANCETP launches 2025 guideline for Algorithmic Treatment of Schizophrenia
New international guidelines emphasize proactive metabolic health management from treatment initiation and earlier consideration of clozapine.
Heparin Dosing, ACT Monitoring Not Linked to Improved Outcomes After LEB
A large study suggests routine activated clotting time monitoring during lower extremity bypass may not improve patient outcomes.
HFpEF Patients Exhibit Higher Respiratory Muscle Oxygen Cost During Submaximal Exercise
A study reveals that individuals with heart failure with preserved ejection fraction expend significantly more oxygen for breathing during exertion.
Pediatric Burn Length of Stay Lower Than Traditional Benchmarks
A multi-institutional analysis of 1,543 pediatric burn patients updates expected hospital stay per TBSA, identifying key influencing factors.
Most Chronic Cough Patients Do Not Achieve Patient-Defined Control Post-Treatment
A single-center observational study established patient-anchored criteria for cough control, finding only 26% of patients met them.
Fibrin Binding Explains Reduced Circulating Myosin After Trauma
Direct binding of skeletal muscle myosin to fibrin clots may clarify its role in trauma-induced coagulopathy and observed plasma level changes.
Ibrutinib Response in WM Linked to Clonal Evolution, T-Cell Dynamics
A single-cell analysis reveals distinct tumor evolution patterns and immune cell changes predicting ibrutinib outcomes in Waldenström macroglobulinemi
Anti-C5a Antibody STSA-1002 Shows Favorable Safety, Reduced Mortality in ARDS
A phase 1b/2 trial indicates STSA-1002 is well tolerated and associated with lower 28-day mortality in viral pneumonia-induced ARDS.
ACEP launches 2025 clinical policy for Endotracheal Intubation in the Emergency Department
The new guideline prioritizes physiologic optimization, recommending noninvasive ventilation for preoxygenation and specific induction agents.