Short Appendiceal Stump on CT Predicts Complex Resection and Open Conversion
A retrospective review found that a stump length under 2 cm increases the odds of extended resection twenty-fold in complicated cases.
Standardized Protocols Reduce Length of Stay in Cushing Disease
A multicenter study of 832 patients shows that formal clinical pathways and non-narcotic pain regimens lower readmission risk.
AI Model Predicts Glioblastoma Infiltration Beyond Visible Tumor Margins
A prospective trial validates an AI tool using biopsies to map microscopic tumor spread and predict survival in glioblastoma patients.
Buprenorphine Initiation Succeeds in 71% of Opioid-Tolerant Cancer Patients
A retrospective study shows transdermal and buccal buprenorphine reduce pain scores with low rates of precipitated withdrawal.
AI Model Predicts Axillary Response Using Baseline Mammography
A deep learning tool identifies nodal conversion after neoadjuvant therapy, potentially reducing unnecessary axillary dissections.
Isolated MPFL Reconstruction Stabilizes Patella Despite High Femoral Anteversion
Patients with femoral torsion over 30 degrees and minimal maltracking achieved stability without derotational osteotomy in a 2-year study.
Polymeric Clips Match Stapler Safety at Lower Cost in Appendectomy
A retrospective study of 692 patients shows polymeric clips are a cost-effective alternative to staplers for appendiceal stump closure.
Danish Registry Data Show Rising ADHD Medication Use and Sex Convergence
Prevalence tripled among girls between 2010 and 2023, though they continue to initiate treatment two years later than boys.
Pediatric Knife Fatalities Linked to Deprivation and Prior Social Service Contact
A five-year review of 145 deaths in England identifies high rates of pre-hospital mortality and significant psychosocial vulnerabilities.
Pre-Diagnosis FEV1 Decline Predicts Mortality in Lung Transplant Recipients
A 20-year cohort study shows that the rate of lung function loss before CLAD onset identifies patients at high risk for rapid progression.
Valproate Linked to Higher Mortality in Patients With Dementia and Epilepsy
A Swedish registry study finds lamotrigine and levetiracetam associated with better survival than valproate or carbamazepine.
Vascular Comorbidities Double Mortality Risk in Haploidentical Transplants
A machine-learning analysis identifies a vascular penalty and a three-factor tool to optimize donor selection in allogeneic HCT.