Online Training Increases Fascia Iliaca Block Use for Pediatric Femur Fractures
A web-based module combined with brief hands-on training doubled the rate of ultrasound-guided regional anesthesia in the emergency department.
TXA Linked to Lower Reoperation Odds in Posttonsillectomy Hemorrhage
A multicenter study of 19,572 pediatric encounters shows tranexamic acid use increased to 30% by 2024 and reduced reoperation risk by 34%.
Severe Childhood Malaria Impairs Cognition Up to 15 Years Later
Ugandan children who survive cerebral malaria or severe malarial anemia show persistent cognitive and math deficits up to 15 years later.
Neuropsychiatric Symptoms and CSF Markers Predict General Paresis Outcomes
A 12-month study identifies depression, apathy, and baseline inflammatory markers as key indicators of prognosis in neurosyphilis.
Antipsychotics Rarely Cause Persistent QTc Prolongation in Children and Adolescents
A cohort study of 430 pediatric patients found no severe arrhythmias or QTc intervals over 500 ms during antipsychotic treatment.
C4A Complement Pathway Decouples from C1Q in First-Episode Psychosis
A study of 113 patients shows that C4A levels shift independently of C4B in the cerebrospinal fluid during early-stage psychosis.
Exogenous Hormones Associate With Reduced Dementia Risk in UK Biobank Cohort
Use of oral contraceptives and hormone replacement therapy correlates with lower rates of Alzheimer's disease and vascular dementia.
Clinical Criteria for LATE Distinguish Cognitive Trajectories from Alzheimer Disease
A study of 3,606 patients shows isolated LATE progresses slower than Alzheimer disease, while comorbid pathology accelerates decline.
Distinct Cortical Thickness Patterns Define Positive and Negative Schizotypy
MRI analysis of 2730 healthy adults links subclinical traits to specific neurotransmitter systems and neurodevelopmental disorders.
Ceruloplasmin Deficiency Linked to Fusiform Gyrus Pathology in Autism Subtype
Low ceruloplasmin levels drive lipid and myelin imbalances in children with autism and atypical visual processing.
Apixaban Reduces Recurrent Stroke in Patients Without High-Risk Hypertension
An ARCADIA trial analysis shows apixaban is more effective than aspirin only when severe hypertension and cardiac hypertrophy are absent.
Cannabis Use Blunts Neurocognitive Development in Adolescents
Longitudinal data and hair toxicology link THC exposure to flattened growth in memory and processing speed from ages 9 to 17.