Cerebrotendinous Xanthomatosis Drives Recurrent Stroke After PFO Closure
A 23-year-old's recurrent M1 occlusion reveals how metabolic drivers of premature atherosclerosis can mimic or coexist with structural defects.
Prefrontal Cortex Origin for Rhythmic Ictal Nonclonic Hand Motions
Intracerebral recordings show that specific hand motions often linked to temporal lobe epilepsy can originate in the middle frontal gyrus.
Xq28 Duplication Involving MECP2 Drives Multisystemic X-Linked Disability
A familial case report identifies a six-gene duplication at Xq28 causing severe neurological and cutaneous symptoms in males.
Auricular Vagus Nerve Stimulation Manages Refractory Sympathetic Hyperactivity Post-Hemorrhage
Adjunctive neuromodulation improved tachypnea and consciousness while reducing polypharmacy in a patient with intracerebral hemorrhage.
Host Antibodies and Bacterial Heteroresistance Drive Phage Therapy Failure
Pre-existing anti-prophage antibodies and bacterial subpopulations with reduced susceptibility may neutralize therapeutic bacteriophages.
Endovascular Stent-Graft Repairs Iatrogenic Subclavian Vein Injury
A 60-year-old patient maintains vessel patency two years after emergency endovascular treatment for a life-threatening venous perforation.
Guillain-Barré Syndrome Presents as Catatonic Stupor in Schizophrenia Case
Diminished tendon reflexes and albuminocytologic dissociation distinguish neurologic paralysis from psychiatric immobility.
Kennedy Infant Death Accelerated Neonatal Research and Halved Mortality Rates
The 1963 loss of Patrick Bouvier Kennedy catalyzed federal funding that transformed respiratory distress syndrome into a survivable condition.
Pseudomonas oryzihabitans Causes Carotid Pseudoaneurysm After Respiratory Infection
A 78-year-old patient developed a life-threatening internal carotid artery lesion three weeks after an untreated common cold.
Venlafaxine Linked to Probable Induction of De Novo Vocal Tics
A case report identifies the first instance of vocal tics following SNRI use, likely due to fronto-striatal dopamine dysregulation.
Electroconvulsive Therapy Aids Personality Integration in Adolescent Dissociative Identity Disorder
A case report details how combined neuromodulation and pharmacotherapy resolved three distinct personality states and severe depression.