Annals of Internal Medicine
Randomized Controlled Trial
Single Sigmoidoscopy Reduces Male Colorectal Cancer Death at 23 Years
A Norwegian trial shows a single screening sigmoidoscopy provides long-term protection for men, but mortality benefits are absent in women.
Annals of Internal Medicine
Randomized Controlled Trial
One-Liter PEG-Ascorbate Improves High-Quality Inpatient Bowel Cleansing
A randomized trial shows very low-volume preparation yields superior right-colon visualization compared to 2-liter and 4-liter regimens.
Annals of Internal Medicine
Randomized Controlled Trial
Proximal Nerve Stimulation Improves Sleep Apnea in CPAP-Intolerant Patients
A randomized trial shows proximal hypoglossal nerve stimulation significantly reduces apnea-hypopnea index and daytime sleepiness.
Annals of Internal Medicine
Randomized Controlled Trial
Physical Therapy Improves Function More Than CBT in Chronic Low Back Pain
A sequential randomized trial finds physical therapy superior for initial functional gains, though secondary strategies show no difference.