The Briefing · Psychiatry & Cognitive Neurology
Continuous newsroom coverage of evidence in Psychiatry & Cognitive Neurology — newest first.
LEAD STORY
Most Common Mental Disorder Interventions Lack Robust Evidence
A systematic review of Cochrane data reveals that less than a quarter of interventions for common mental disorders have high or moderate quality evide
Top stories
Yesterday
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Acetate Attenuates Microglial Inflammation in Traumatic Brain Injury Model, Not Sepsis
Physiological doses of the gut metabolite acetate reduced inflammatory markers in an in vitro TBI model, but not in a sepsis model.
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Autonomic Burden Linked to Cognitive Fluctuations in Lewy Body Dementia
A longitudinal study finds autonomic symptom severity correlates with neuropsychiatric burden and reduced caregiver quality of life.
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Anterior Temporal Atrophy Precedes Semantic Dementia Symptoms by Five Years
Large-scale MRI analysis identifies a prolonged prodromal phase and quantifies the prevalence of incidental anterior temporal lobe loss.
This week
17 stories-
Amateur Soccer Heading Linked to Acute Elevations in Neural Damage Biomarkers
A prospective study found that heading in amateur soccer acutely increases blood levels of p-tau217 and S100B, with dose-response relationships.
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Cervical Spinal Cord Injury Linked to Higher Depression Risk Than Lower-Level Injuries
A nationwide cohort study reveals patients with cervical SCI face a significantly elevated risk of depression compared to those with thoracic/lumbar.
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Real-World Data Predicts Long-Term Poor Outcomes in Clinical High-Risk Psychosis
A new model identifies individuals at clinical high risk for psychosis who face diverse long-term adverse events, including hospitalization and suicid
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MEG Reveals Specific Brain and Autonomic Changes in PTSD Affective Processing
Electrophysiological and heart rhythm markers identify altered affective processing in service members with post-traumatic stress disorder.
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Continuous EEG Enhances Detection of Post-Stroke Epilepsy Predictors
A retrospective study shows continuous EEG significantly improves identification of epileptiform activity and prediction of post-stroke epilepsy.
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Cingulum Hippocampus White Matter Integrity Linked to Suicide Attempts in Bipolar Disorder
Reduced fractional anisotropy in the cingulum hippocampus, mediated by impulsivity, associates with suicide attempts in bipolar disorder.
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Accelerometer Data Predicts Dementia Risk in Older Adults
Objective sleep-wake cycle metrics from wearables modestly enhance dementia risk prediction, comparable to APOE genotype.
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CANMAT launches 2024 guideline for Major Depressive Disorder Management
The updated CANMAT guideline extends recommended antidepressant maintenance duration and emphasizes earlier adjunctive strategies for limited.
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CANMAT launches 2024 guideline for Perinatal Mood, Anxiety, and Related Disorders
The new CANMAT guideline emphasizes routine, systematic screening for perinatal mood and anxiety disorders throughout pregnancy and up to one year.
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ASAM launches Joint Clinical Practice Guideline on Benzodiazepine Tapering
This new guideline emphasizes patient-centered, gradual benzodiazepine tapering, with a strong caution against abrupt discontinuation due.
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LANCETP launches 2025 guideline for Algorithmic Treatment of Schizophrenia
New international guidelines emphasize proactive metabolic health management from treatment initiation and earlier consideration of clozapine.
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AA and SNMMI launch 2025 guideline for Amyloid and Tau PET Appropriate Use Criteria
New guidelines expand appropriate use of amyloid and tau PET, particularly for eligibility and monitoring of amyloid-targeting therapies.
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Alzheimer's Association launches 2024 guideline for Alzheimer's disease and related dementias
New guidance empowers primary care clinicians with a structured, patient-centered approach to diagnostic evaluation, testing, counseling.
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Global Efforts Advance Human Rights Protections for Older Adults' Mental Health
International bodies and national initiatives are establishing frameworks to safeguard the dignity and mental well-being of the aging population.
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Tea Polyphenols Mitigate Brain Changes, Anxiety in Aged Diabetic Rats
A preclinical study in aged T2DM rats suggests tea polyphenol intervention may improve hippocampal structure, function, and behavior.
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Diffuse White Matter Abnormalities Do Not Predict Long-Term Dementia Risk
A 10-year study finds that 'dirty-appearing' white matter lacks the prognostic weight of focal hyperintensities in older adults.
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Lamotrigine-Topiramate Duotherapy Increases Congenital Malformation Risk Fourfold
A large registry study identifies a significant risk increase for specific antiseizure drug combinations used during the first trimester.